Interaction and Collaboration of SP1, HIF-1, and MYC in Regulating the Expression of Cancer-Related Genes to Further Enhance Anticancer Drug Development

Interaction and Collaboration of SP1, HIF-1, and MYC in Regulating the Expression of Cancer-Related Genes to Further Enhance Anticancer Drug Development

Specificity protein 1 (SP1), hypoxia-inducible factor 1 (HIF-1), and MYC are important transcription factors (TFs). SP1, a constitutively expressed housekeeping gene, regulates diverse yet distinct biological activities; MYC is a master regulator of all key cellular activities including cell metabol...

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Bibliographic Details
Main Authors: Kotohiko Kimura, Tiffany L. B. Jackson, Ru Chih C. Huang
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Current Issues in Molecular Biology
Subjects:
hypoxia-inducible factor 1
SP1
MYC
cancer
Online Access:https://www.mdpi.com/1467-3045/45/11/580

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