Expanding TAVI to Low and Intermediate Risk Patients

TAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges—particularly with regard to valve durabili...

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Main Authors: Lisa Voigtländer, Moritz Seiffert
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00092/full
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author Lisa Voigtländer
Moritz Seiffert
Moritz Seiffert
author_facet Lisa Voigtländer
Moritz Seiffert
Moritz Seiffert
author_sort Lisa Voigtländer
collection DOAJ
description TAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges—particularly with regard to valve durability—need to be addressed before expansion to lower risk and younger patients can be recommended on a broad basis. Current trends, trials results, and remaining challenges are summarized and discussed in the light of updated treatment guidelines.
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spelling doaj.art-8df93c64b6ca4d39a845d968bcc88c7c2022-12-21T21:52:30ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2018-07-01510.3389/fcvm.2018.00092380580Expanding TAVI to Low and Intermediate Risk PatientsLisa Voigtländer0Moritz Seiffert1Moritz Seiffert2Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, GermanyDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, GermanyPartner site Hamburg/Kiel/Lübeck, DZHK, German Centre for Cardiovascular Research, Hamburg, GermanyTAVI has become the standard treatment in patients at increased surgical risk and is increasingly being performed in patients at intermediate to low surgical risk. While non-inferiority has been demonstrated in intermediate risk patients, several challenges—particularly with regard to valve durability—need to be addressed before expansion to lower risk and younger patients can be recommended on a broad basis. Current trends, trials results, and remaining challenges are summarized and discussed in the light of updated treatment guidelines.https://www.frontiersin.org/article/10.3389/fcvm.2018.00092/fullTAVITAVRintermediate risklow riskaortic valve stenosis
spellingShingle Lisa Voigtländer
Moritz Seiffert
Moritz Seiffert
Expanding TAVI to Low and Intermediate Risk Patients
Frontiers in Cardiovascular Medicine
TAVI
TAVR
intermediate risk
low risk
aortic valve stenosis
title Expanding TAVI to Low and Intermediate Risk Patients
title_full Expanding TAVI to Low and Intermediate Risk Patients
title_fullStr Expanding TAVI to Low and Intermediate Risk Patients
title_full_unstemmed Expanding TAVI to Low and Intermediate Risk Patients
title_short Expanding TAVI to Low and Intermediate Risk Patients
title_sort expanding tavi to low and intermediate risk patients
topic TAVI
TAVR
intermediate risk
low risk
aortic valve stenosis
url https://www.frontiersin.org/article/10.3389/fcvm.2018.00092/full
work_keys_str_mv AT lisavoigtlander expandingtavitolowandintermediateriskpatients
AT moritzseiffert expandingtavitolowandintermediateriskpatients
AT moritzseiffert expandingtavitolowandintermediateriskpatients