Pituitary Function Impairment after Moderate Traumatic Brain Injury

To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007....

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Main Authors: Mohammad Reza Hadji Abadi, Mohammad Ghodsi, Masoud Merazin, Hadi Roozbeh
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2011-07-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/3771
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author Mohammad Reza Hadji Abadi
Mohammad Ghodsi
Masoud Merazin
Hadi Roozbeh
author_facet Mohammad Reza Hadji Abadi
Mohammad Ghodsi
Masoud Merazin
Hadi Roozbeh
author_sort Mohammad Reza Hadji Abadi
collection DOAJ
description To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007. Pituitary hormones were assessed 3 and 6 months after injury. In 3rd month post-injury, 39 cases had not any pituitary dysfunction; however, deficiencies in one, two and three of the pituitary hormones were found in 26, 8 and 2 patients, respectively. Twenty one patients showed a deficiency in one of the pituitary hormones and only one case with deficiency of two after 6 months. The most prevalent changes occur in IGF-1 and LH/FSH after moderate TBI. However, the whole deficiencies decrease over the time.
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spelling doaj.art-8dfb4e8533fa4b29abcf83132b3645142022-12-22T03:18:04ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942011-07-01497Pituitary Function Impairment after Moderate Traumatic Brain InjuryMohammad Reza Hadji Abadi0Mohammad Ghodsi1Masoud Merazin2Hadi Roozbeh3Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007. Pituitary hormones were assessed 3 and 6 months after injury. In 3rd month post-injury, 39 cases had not any pituitary dysfunction; however, deficiencies in one, two and three of the pituitary hormones were found in 26, 8 and 2 patients, respectively. Twenty one patients showed a deficiency in one of the pituitary hormones and only one case with deficiency of two after 6 months. The most prevalent changes occur in IGF-1 and LH/FSH after moderate TBI. However, the whole deficiencies decrease over the time.https://acta.tums.ac.ir/index.php/acta/article/view/3771TBIPituitary hormoneModerate injury
spellingShingle Mohammad Reza Hadji Abadi
Mohammad Ghodsi
Masoud Merazin
Hadi Roozbeh
Pituitary Function Impairment after Moderate Traumatic Brain Injury
Acta Medica Iranica
TBI
Pituitary hormone
Moderate injury
title Pituitary Function Impairment after Moderate Traumatic Brain Injury
title_full Pituitary Function Impairment after Moderate Traumatic Brain Injury
title_fullStr Pituitary Function Impairment after Moderate Traumatic Brain Injury
title_full_unstemmed Pituitary Function Impairment after Moderate Traumatic Brain Injury
title_short Pituitary Function Impairment after Moderate Traumatic Brain Injury
title_sort pituitary function impairment after moderate traumatic brain injury
topic TBI
Pituitary hormone
Moderate injury
url https://acta.tums.ac.ir/index.php/acta/article/view/3771
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AT mohammadghodsi pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury
AT masoudmerazin pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury
AT hadiroozbeh pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury