Pituitary Function Impairment after Moderate Traumatic Brain Injury
To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007....
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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Tehran University of Medical Sciences
2011-07-01
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Series: | Acta Medica Iranica |
Subjects: | |
Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3771 |
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author | Mohammad Reza Hadji Abadi Mohammad Ghodsi Masoud Merazin Hadi Roozbeh |
author_facet | Mohammad Reza Hadji Abadi Mohammad Ghodsi Masoud Merazin Hadi Roozbeh |
author_sort | Mohammad Reza Hadji Abadi |
collection | DOAJ |
description | To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007. Pituitary hormones were assessed 3 and 6 months after injury. In 3rd month post-injury, 39 cases had not any pituitary dysfunction; however, deficiencies in one, two and three of the pituitary hormones were found in 26, 8 and 2 patients, respectively. Twenty one patients showed a deficiency in one of the pituitary hormones and only one case with deficiency of two after 6 months. The most prevalent changes occur in IGF-1 and LH/FSH after moderate TBI. However, the whole deficiencies decrease over the time. |
first_indexed | 2024-04-12T20:18:17Z |
format | Article |
id | doaj.art-8dfb4e8533fa4b29abcf83132b364514 |
institution | Directory Open Access Journal |
issn | 0044-6025 1735-9694 |
language | English |
last_indexed | 2024-04-12T20:18:17Z |
publishDate | 2011-07-01 |
publisher | Tehran University of Medical Sciences |
record_format | Article |
series | Acta Medica Iranica |
spelling | doaj.art-8dfb4e8533fa4b29abcf83132b3645142022-12-22T03:18:04ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942011-07-01497Pituitary Function Impairment after Moderate Traumatic Brain InjuryMohammad Reza Hadji Abadi0Mohammad Ghodsi1Masoud Merazin2Hadi Roozbeh3Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007. Pituitary hormones were assessed 3 and 6 months after injury. In 3rd month post-injury, 39 cases had not any pituitary dysfunction; however, deficiencies in one, two and three of the pituitary hormones were found in 26, 8 and 2 patients, respectively. Twenty one patients showed a deficiency in one of the pituitary hormones and only one case with deficiency of two after 6 months. The most prevalent changes occur in IGF-1 and LH/FSH after moderate TBI. However, the whole deficiencies decrease over the time.https://acta.tums.ac.ir/index.php/acta/article/view/3771TBIPituitary hormoneModerate injury |
spellingShingle | Mohammad Reza Hadji Abadi Mohammad Ghodsi Masoud Merazin Hadi Roozbeh Pituitary Function Impairment after Moderate Traumatic Brain Injury Acta Medica Iranica TBI Pituitary hormone Moderate injury |
title | Pituitary Function Impairment after Moderate Traumatic Brain Injury |
title_full | Pituitary Function Impairment after Moderate Traumatic Brain Injury |
title_fullStr | Pituitary Function Impairment after Moderate Traumatic Brain Injury |
title_full_unstemmed | Pituitary Function Impairment after Moderate Traumatic Brain Injury |
title_short | Pituitary Function Impairment after Moderate Traumatic Brain Injury |
title_sort | pituitary function impairment after moderate traumatic brain injury |
topic | TBI Pituitary hormone Moderate injury |
url | https://acta.tums.ac.ir/index.php/acta/article/view/3771 |
work_keys_str_mv | AT mohammadrezahadjiabadi pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury AT mohammadghodsi pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury AT masoudmerazin pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury AT hadiroozbeh pituitaryfunctionimpairmentaftermoderatetraumaticbraininjury |