Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?
Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal pos...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/8/1120 |
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| author | Lehlogonolo N. F. Maphalle Bozena B. Michniak-Kohn Modupe O. Ogunrombi Oluwatoyin A. Adeleke |
| author_facet | Lehlogonolo N. F. Maphalle Bozena B. Michniak-Kohn Modupe O. Ogunrombi Oluwatoyin A. Adeleke |
| author_sort | Lehlogonolo N. F. Maphalle |
| collection | DOAJ |
| description | Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal post-infection or even serve as reservoirs for future disease outbreaks. However, pediatric TB is the least prioritized in most health programs and optimal infection/disease control has been quite neglected for this specialized patient category, as most scientific and clinical research efforts focus on developing novel management strategies for adults. Moreover, the ongoing coronavirus pandemic has meaningfully hindered the gains and progress achieved with TB prophylaxis, therapy, diagnosis, and global eradication goals for all affected persons of varying age bands. Thus, the opening of novel research activities and opportunities that can provide more insight and create new knowledge specifically geared towards managing TB disease in this specialized group will significantly improve their well-being and longevity. |
| first_indexed | 2024-03-09T09:59:39Z |
| format | Article |
| id | doaj.art-8dfff792a1f847b59d56839a5a5bf678 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T09:59:39Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-8dfff792a1f847b59d56839a5a5bf6782023-12-01T23:34:03ZengMDPI AGChildren2227-90672022-07-0198112010.3390/children9081120Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?Lehlogonolo N. F. Maphalle0Bozena B. Michniak-Kohn1Modupe O. Ogunrombi2Oluwatoyin A. Adeleke3Division of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0208, South AfricaErnest Mario School of Pharmacy, Rutgers-The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USADepartment of Clinical Pharmacology and Therapeutics, Sefako Makgatho Health Science University, Pretoria 0208, South AfricaDivision of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0208, South AfricaManaging pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill health and death in children as well as adolescents universally. Minors are particularly susceptible to this severe illness that can be fatal post-infection or even serve as reservoirs for future disease outbreaks. However, pediatric TB is the least prioritized in most health programs and optimal infection/disease control has been quite neglected for this specialized patient category, as most scientific and clinical research efforts focus on developing novel management strategies for adults. Moreover, the ongoing coronavirus pandemic has meaningfully hindered the gains and progress achieved with TB prophylaxis, therapy, diagnosis, and global eradication goals for all affected persons of varying age bands. Thus, the opening of novel research activities and opportunities that can provide more insight and create new knowledge specifically geared towards managing TB disease in this specialized group will significantly improve their well-being and longevity.https://www.mdpi.com/2227-9067/9/8/1120pediatricspulmonary tuberculosisextrapulmonary tuberculosisdiagnosistreatmentprevention |
| spellingShingle | Lehlogonolo N. F. Maphalle Bozena B. Michniak-Kohn Modupe O. Ogunrombi Oluwatoyin A. Adeleke Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? Children pediatrics pulmonary tuberculosis extrapulmonary tuberculosis diagnosis treatment prevention |
| title | Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? |
| title_full | Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? |
| title_fullStr | Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? |
| title_full_unstemmed | Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? |
| title_short | Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? |
| title_sort | pediatric tuberculosis management a global challenge or breakthrough |
| topic | pediatrics pulmonary tuberculosis extrapulmonary tuberculosis diagnosis treatment prevention |
| url | https://www.mdpi.com/2227-9067/9/8/1120 |
| work_keys_str_mv | AT lehlogonolonfmaphalle pediatrictuberculosismanagementaglobalchallengeorbreakthrough AT bozenabmichniakkohn pediatrictuberculosismanagementaglobalchallengeorbreakthrough AT modupeoogunrombi pediatrictuberculosismanagementaglobalchallengeorbreakthrough AT oluwatoyinaadeleke pediatrictuberculosismanagementaglobalchallengeorbreakthrough |