Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor
Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
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| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506123000983 |
| _version_ | 1827937810532794368 |
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| author | Niharika Patlolla Pretty Ponnachan Colin Jamora Deepti Abbey |
| author_facet | Niharika Patlolla Pretty Ponnachan Colin Jamora Deepti Abbey |
| author_sort | Niharika Patlolla |
| collection | DOAJ |
| description | Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after episomal reprogramming of PBMCs. The generated line is pluripotent, had normal karyotype and has a potential of tri-lineage differentiation. The generated line would serve as control line of Asian origin from Indian population. |
| first_indexed | 2024-03-13T08:30:02Z |
| format | Article |
| id | doaj.art-8e0228b4d3fe4a40b165839712008d17 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-03-13T08:30:02Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-8e0228b4d3fe4a40b165839712008d172023-05-31T04:44:14ZengElsevierStem Cell Research1873-50612023-06-0169103112Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donorNiharika Patlolla0Pretty Ponnachan1Colin Jamora2Deepti Abbey3Institute for Stem Cell Science and Regenerative Medicine, (inStem), Bangalore, India; Current affiliation: Eyestem Research, Centre for Cellular and Molecular Platforms (C-CAMP), Bengaluru, IndiaInstitute for Stem Cell Science and Regenerative Medicine, (inStem), Bangalore, IndiaInstitute for Stem Cell Science and Regenerative Medicine, (inStem), Bangalore, IndiaInstitute for Stem Cell Science and Regenerative Medicine, (inStem), Bangalore, India; Current affiliation: Indian Institute of Technology-Delhi, Hauz Khas, Delhi 110016, India; Corresponding author at: Institute for Stem Cell Science and Regenerative Medicine, (inStem), Bangalore, India.Human pluripotent stem cells serve as a robust model system to study disease pathogenesis in a dish and search for various targeted therapeutics. Collection of control lines from healthy individuals are essential for any study. Therefore, we have generated hiPSC line from a healthy male donor after episomal reprogramming of PBMCs. The generated line is pluripotent, had normal karyotype and has a potential of tri-lineage differentiation. The generated line would serve as control line of Asian origin from Indian population.http://www.sciencedirect.com/science/article/pii/S1873506123000983 |
| spellingShingle | Niharika Patlolla Pretty Ponnachan Colin Jamora Deepti Abbey Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor Stem Cell Research |
| title | Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor |
| title_full | Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor |
| title_fullStr | Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor |
| title_full_unstemmed | Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor |
| title_short | Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor |
| title_sort | generation of control human ipsc line instemi001 a from pbmcs of a healthy indian donor |
| url | http://www.sciencedirect.com/science/article/pii/S1873506123000983 |
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