Interferon-γ-inducible protein 16 (IFI16) is required for the maintenance of Epstein-Barr virus latency

Interferon-γ-inducible protein 16 (IFI16) is required for the maintenance of Epstein-Barr virus latency

Abstract Background Epstein-Barr virus (EBV) exhibits both lytic and latent (Lat. I, II, and III) phases in an infected individual. It’s during the latent phase of EBV that all EBV-associated cancers, including Burkitt’s lymphoma, nasopharyngeal carcinoma and lymphoproliferative disease arise. Inter...

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Bibliographic Details
Main Authors: Gina Pisano, Arunava Roy, Mairaj Ahmed Ansari, Binod Kumar, Leela Chikoti, Bala Chandran
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Virology Journal
Subjects:
Epstein-Barr virus (EBV)
Interferon-γ-inducible protein 16 (IFI16)
Herpesvirus
Latency
Lytic cycle
Online Access:http://link.springer.com/article/10.1186/s12985-017-0891-5

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