Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer

Abstract Glycosylation is a common posttranslational modification on membrane-associated and secreted proteins that is of pivotal importance for regulating cell functions. Aberrant glycosylation can lead to uncontrolled cell proliferation, cell-matrix interactions, migration and differentiation, and...

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Bibliographic Details
Main Authors: Jing Zhang, Peter ten Dijke, Manfred Wuhrer, Tao Zhang
Format: Article
Language:English
Published: Oxford University Press 2020-06-01
Series:Protein & Cell
Subjects:
Online Access:https://doi.org/10.1007/s13238-020-00741-7