Syndecan-1-Induced ECM Fiber Alignment Requires Integrin αvβ3 and Syndecan-1 Ectodomain and Heparan Sulfate Chains.
Expression of the cell surface proteoglycan syndecan-1 (Sdc1) is frequently induced in stromal fibroblasts of invasive breast carcinomas. We have recently identified a correlation between stromal Sdc1 expression and extracellular matrix (ECM) fiber alignment, both in vitro and in vivo. ECMs derived...
Main Authors: | Ning Yang, Andreas Friedl |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4766302?pdf=render |
Similar Items
-
Regulated Shedding of Syndecan Ectodomains by Chemokines
by: Nathalie Charnaux, et al.
Published: (2006-01-01) -
Mapping the Interactome of the Nuclear Heparan Sulfate Proteoglycan Syndecan-1 in Mesothelioma Cells
by: Ashish Kumar-Singh, et al.
Published: (2020-07-01) -
The role of syndecan-1 in cellular signaling and its effects on heparan sulfate biosynthesis in mesenchymal tumors
by: Tünde eSzatmári, et al.
Published: (2013-12-01) -
<a name="home"></a>Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling
by: C.C. Lopes, et al.
Published: (2006-02-01) -
The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis
by: Melanie Timmen, et al.
Published: (2020-11-01)