Role of Lipids and Divalent Cations in Membrane Fusion Mediated by the Heptad Repeat Domain 1 of Mitofusin

Role of Lipids and Divalent Cations in Membrane Fusion Mediated by the Heptad Repeat Domain 1 of Mitofusin

Mitochondria are highly dynamic organelles that constantly undergo fusion and fission events to maintain their shape, distribution and cellular function. Mitofusin 1 and 2 proteins are two dynamin-like GTPases involved in the fusion of outer mitochondrial membranes (OMM). Mitofusins are anchored to...

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Bibliographic Details
Main Authors: Anaïs Vlieghe, Kristina Niort, Hugo Fumat, Jean-Michel Guigner, Mickaël M. Cohen, David Tareste
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
mitochondria
membrane
fusion
Mitofusin
amphipathic helix
divalent cations
Online Access:https://www.mdpi.com/2218-273X/13/9/1341

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