Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely
We aimed to investigate the relation between the time intervals of the flow velocity waveform of ductus venosus (DV-FVW) and cardiac cycles. We defined Delta A as the difference in the time measurements between DV-FVW and cardiac cycles on the assumption that the second peak of ductus venosus (D-wav...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/6/1393 |
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| author | Naomi Seo Yasushi Kurihara Tomoki Suekane Natsuko Yokoi Kayoko Nakagawa Mie Tahara Akihiro Hamuro Takuya Misugi Akemi Nakano Masayasu Koyama Daisuke Tachibana |
| author_facet | Naomi Seo Yasushi Kurihara Tomoki Suekane Natsuko Yokoi Kayoko Nakagawa Mie Tahara Akihiro Hamuro Takuya Misugi Akemi Nakano Masayasu Koyama Daisuke Tachibana |
| author_sort | Naomi Seo |
| collection | DOAJ |
| description | We aimed to investigate the relation between the time intervals of the flow velocity waveform of ductus venosus (DV-FVW) and cardiac cycles. We defined Delta A as the difference in the time measurements between DV-FVW and cardiac cycles on the assumption that the second peak of ductus venosus (D-wave) starts simultaneously with the opening of the mitral valve (MV). As well, we defined Delta B as the difference of the time measurements between DV-FVW and cardiac cycles on the assumption that the D-wave starts simultaneously with the closure of the aortic valve (AV). We then compared Delta A and Delta B in the control and fetal growth restriction (FGR) groups. In the control group of healthy fetuses, Delta A was strikingly shorter than Delta B. On the other hand, in all FGR cases, no difference was observed. The acceleration of the D-wave is suggested to be generated by the opening of the MV under normal fetal hemodynamics, whereas it precedes the opening of the MV in FGR. Our results indicate that the time interval of DV analysis might be a more informative parameter than the analysis of cardiac cycles. |
| first_indexed | 2024-03-10T00:00:32Z |
| format | Article |
| id | doaj.art-8e144e2cfbac49a08695a44ae9d19a08 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T00:00:32Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-8e144e2cfbac49a08695a44ae9d19a082023-11-23T16:17:25ZengMDPI AGDiagnostics2075-44182022-06-01126139310.3390/diagnostics12061393Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More PreciselyNaomi Seo0Yasushi Kurihara1Tomoki Suekane2Natsuko Yokoi3Kayoko Nakagawa4Mie Tahara5Akihiro Hamuro6Takuya Misugi7Akemi Nakano8Masayasu Koyama9Daisuke Tachibana10Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Gynecology, Saiseikai Senri Hospital Based On Social Welfare Organization Saiseikai Imperial Gift Foundation, 1-1-6 Tsukumodai, Suita-shi 565-0862, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Izumiotsu City Hospital, 16-1 Gezyocho Izumiotsu, Osaka 595-0027, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanDepartment of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, JapanWe aimed to investigate the relation between the time intervals of the flow velocity waveform of ductus venosus (DV-FVW) and cardiac cycles. We defined Delta A as the difference in the time measurements between DV-FVW and cardiac cycles on the assumption that the second peak of ductus venosus (D-wave) starts simultaneously with the opening of the mitral valve (MV). As well, we defined Delta B as the difference of the time measurements between DV-FVW and cardiac cycles on the assumption that the D-wave starts simultaneously with the closure of the aortic valve (AV). We then compared Delta A and Delta B in the control and fetal growth restriction (FGR) groups. In the control group of healthy fetuses, Delta A was strikingly shorter than Delta B. On the other hand, in all FGR cases, no difference was observed. The acceleration of the D-wave is suggested to be generated by the opening of the MV under normal fetal hemodynamics, whereas it precedes the opening of the MV in FGR. Our results indicate that the time interval of DV analysis might be a more informative parameter than the analysis of cardiac cycles.https://www.mdpi.com/2075-4418/12/6/1393fetal growth restrictionductus venosuscardiac cycletime-related analysisDoppler |
| spellingShingle | Naomi Seo Yasushi Kurihara Tomoki Suekane Natsuko Yokoi Kayoko Nakagawa Mie Tahara Akihiro Hamuro Takuya Misugi Akemi Nakano Masayasu Koyama Daisuke Tachibana Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely Diagnostics fetal growth restriction ductus venosus cardiac cycle time-related analysis Doppler |
| title | Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely |
| title_full | Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely |
| title_fullStr | Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely |
| title_full_unstemmed | Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely |
| title_short | Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely |
| title_sort | altered transmission of cardiac cycles to ductus venosus blood flow in fetal growth restriction why ductus venosus reflects fetal circulatory changes more precisely |
| topic | fetal growth restriction ductus venosus cardiac cycle time-related analysis Doppler |
| url | https://www.mdpi.com/2075-4418/12/6/1393 |
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