Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation
Intravesical bacillus Calmette-Guerin (BCG) instillation is an effective treatment for nonmuscle invasive superficial bladder cancer. BCG induces a massive influx of inflammatory cells and production of cytokines in the bladder mucosa and lumen that leads to an immune response against tumor cells, a...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Craniovertebral Junction and Spine |
| Subjects: | |
| Online Access: | http://www.jcvjs.com/article.asp?issn=0974-8237;year=2021;volume=12;issue=3;spage=318;epage=321;aulast= |
| _version_ | 1819131088950263808 |
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| author | Hiroki Ohata David Prakasa Hiroyuki Goto Kenji Ohata Takeo Goto Misao Nishikawa |
| author_facet | Hiroki Ohata David Prakasa Hiroyuki Goto Kenji Ohata Takeo Goto Misao Nishikawa |
| author_sort | Hiroki Ohata |
| collection | DOAJ |
| description | Intravesical bacillus Calmette-Guerin (BCG) instillation is an effective treatment for nonmuscle invasive superficial bladder cancer. BCG induces a massive influx of inflammatory cells and production of cytokines in the bladder mucosa and lumen that leads to an immune response against tumor cells, acting as an immunotherapy. Cystitis, bladder ulceration, and bladder contracture are known local genitourinary complications, whereas systemic complications such as miliary pulmonary tuberculosis, mycotic aneurysms, tuberculous spondylodiscitis, and granulomatous hepatitis are very rare.
A case of tuberculous spondylodiscitis at the T8 and T9 levels following intravesical BCG instillation for bladder carcinoma is reported. The patient initially underwent decompressive laminectomy for spastic paraparesis. After reporting improvement for few weeks, the patient again presented with similar complaints and was found to have an increased kyphotic deformity, for which he underwent fixation surgery. |
| first_indexed | 2024-12-22T09:09:57Z |
| format | Article |
| id | doaj.art-8e14e2def4bd482abf2b26a3be567481 |
| institution | Directory Open Access Journal |
| issn | 0974-8237 |
| language | English |
| last_indexed | 2024-12-22T09:09:57Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Craniovertebral Junction and Spine |
| spelling | doaj.art-8e14e2def4bd482abf2b26a3be5674812022-12-21T18:31:27ZengWolters Kluwer Medknow PublicationsJournal of Craniovertebral Junction and Spine0974-82372021-01-0112331832110.4103/jcvjs.jcvjs_201_20Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillationHiroki OhataDavid PrakasaHiroyuki GotoKenji OhataTakeo GotoMisao NishikawaIntravesical bacillus Calmette-Guerin (BCG) instillation is an effective treatment for nonmuscle invasive superficial bladder cancer. BCG induces a massive influx of inflammatory cells and production of cytokines in the bladder mucosa and lumen that leads to an immune response against tumor cells, acting as an immunotherapy. Cystitis, bladder ulceration, and bladder contracture are known local genitourinary complications, whereas systemic complications such as miliary pulmonary tuberculosis, mycotic aneurysms, tuberculous spondylodiscitis, and granulomatous hepatitis are very rare. A case of tuberculous spondylodiscitis at the T8 and T9 levels following intravesical BCG instillation for bladder carcinoma is reported. The patient initially underwent decompressive laminectomy for spastic paraparesis. After reporting improvement for few weeks, the patient again presented with similar complaints and was found to have an increased kyphotic deformity, for which he underwent fixation surgery.http://www.jcvjs.com/article.asp?issn=0974-8237;year=2021;volume=12;issue=3;spage=318;epage=321;aulast=intravesical bacillus calmette-guerinpott's spinetuberculous spondylodiscitis |
| spellingShingle | Hiroki Ohata David Prakasa Hiroyuki Goto Kenji Ohata Takeo Goto Misao Nishikawa Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation Journal of Craniovertebral Junction and Spine intravesical bacillus calmette-guerin pott's spine tuberculous spondylodiscitis |
| title | Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation |
| title_full | Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation |
| title_fullStr | Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation |
| title_full_unstemmed | Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation |
| title_short | Two-stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus Calmette-Guerin instillation |
| title_sort | two stage posterior decompression and fusion for tuberculous spondylitis after intravesical bacillus calmette guerin instillation |
| topic | intravesical bacillus calmette-guerin pott's spine tuberculous spondylodiscitis |
| url | http://www.jcvjs.com/article.asp?issn=0974-8237;year=2021;volume=12;issue=3;spage=318;epage=321;aulast= |
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