Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions
Background and objectives: Today, due to the increasing antibiotic resistance of bacteria, the use of medicinal plants as a suitable alternative to antibiotics has increased significantly; therefore, in this study, the antibacterial effects of methanolic extracts of Staphylococcus aureus, Bacillus c...
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Format: | Article |
Language: | English |
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Golestan University of Medical Sciences
2018-12-01
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Series: | Jorjani Biomedicine Journal |
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Online Access: | http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-506-1&slc_lang=en&sid=1 |
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author | Abolfazl Jafari-Sales Parisa Bolouri |
author_facet | Abolfazl Jafari-Sales Parisa Bolouri |
author_sort | Abolfazl Jafari-Sales |
collection | DOAJ |
description | Background and objectives: Today, due to the increasing antibiotic resistance of bacteria, the use of medicinal plants as a suitable alternative to antibiotics has increased significantly; therefore, in this study, the antibacterial effects of methanolic extracts of Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa and Escherichia coli were evaluated.
Methods: In this laboratory research, after collecting plants and confirming its scientific name, extract of Glycyrrhiza glabra L. Root was prepared by Soxhlet extractor method at concentrations of 20 mg / ml to 400 mg / ml. Then the antimicrobial effects of this extract were investigated using Agar well diffusion and Dilution test methods.
Results: The results showed that the methanolic extracts of G.glabra L. in both Agar well diffusion and Dilution test methods had antibacterial effects on the tested bacteria. The highest effect was observed on S.aureus and the lowest effect was observed in P.aeruginosa.
Conclusion: According to the above results, it can be expected that the G.glabra L. extract can be used to treat bacterial infections and is a suitable alternative to commonly used chemical treatments for the treatment of infections. |
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id | doaj.art-8e14f4d76c344f7186b0391987727e00 |
institution | Directory Open Access Journal |
issn | 2645-3509 |
language | English |
last_indexed | 2024-12-12T04:48:38Z |
publishDate | 2018-12-01 |
publisher | Golestan University of Medical Sciences |
record_format | Article |
series | Jorjani Biomedicine Journal |
spelling | doaj.art-8e14f4d76c344f7186b0391987727e002022-12-22T00:37:33ZengGolestan University of Medical SciencesJorjani Biomedicine Journal2645-35092018-12-01647884Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditionsAbolfazl Jafari-Sales0Parisa Bolouri1 Department of Microbiology School of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran Department of Field Crops, Faculty of Agricalture, Ataturk University, Erzurum, Turkey. Background and objectives: Today, due to the increasing antibiotic resistance of bacteria, the use of medicinal plants as a suitable alternative to antibiotics has increased significantly; therefore, in this study, the antibacterial effects of methanolic extracts of Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa and Escherichia coli were evaluated. Methods: In this laboratory research, after collecting plants and confirming its scientific name, extract of Glycyrrhiza glabra L. Root was prepared by Soxhlet extractor method at concentrations of 20 mg / ml to 400 mg / ml. Then the antimicrobial effects of this extract were investigated using Agar well diffusion and Dilution test methods. Results: The results showed that the methanolic extracts of G.glabra L. in both Agar well diffusion and Dilution test methods had antibacterial effects on the tested bacteria. The highest effect was observed on S.aureus and the lowest effect was observed in P.aeruginosa. Conclusion: According to the above results, it can be expected that the G.glabra L. extract can be used to treat bacterial infections and is a suitable alternative to commonly used chemical treatments for the treatment of infections.http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-506-1&slc_lang=en&sid=1Antimicrobial EffectsExtractMedicinal PlantsPathogenic Bacteria |
spellingShingle | Abolfazl Jafari-Sales Parisa Bolouri Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions Jorjani Biomedicine Journal Antimicrobial Effects Extract Medicinal Plants Pathogenic Bacteria |
title | Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions |
title_full | Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions |
title_fullStr | Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions |
title_full_unstemmed | Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions |
title_short | Evaluation of the antimicrobial effects of Glycyrrhiza glabra l. on some gram positive and gram negative pathogenic bacteria in laboratory conditions |
title_sort | evaluation of the antimicrobial effects of glycyrrhiza glabra l on some gram positive and gram negative pathogenic bacteria in laboratory conditions |
topic | Antimicrobial Effects Extract Medicinal Plants Pathogenic Bacteria |
url | http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-506-1&slc_lang=en&sid=1 |
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