Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran
Summary: Background: Hospital-acquired infections (HAIs) are critical and mostly preventable complications that occur in hospitalized patients and lead to major health and economic burdens. Most of the information on HAI risk factors and the recommended preventive measures is based on data acquired...
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| Format: | Article |
| Language: | English |
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Elsevier
2012-04-01
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| Series: | Journal of Infection and Public Health |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034112000081 |
| _version_ | 1819078927740567552 |
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| author | Mehrdad Askarian Mahnaz Yadollahi Ojan Assadian |
| author_facet | Mehrdad Askarian Mahnaz Yadollahi Ojan Assadian |
| author_sort | Mehrdad Askarian |
| collection | DOAJ |
| description | Summary: Background: Hospital-acquired infections (HAIs) are critical and mostly preventable complications that occur in hospitalized patients and lead to major health and economic burdens. Most of the information on HAI risk factors and the recommended preventive measures is based on data acquired from only a few countries. The aim of this point prevalence HAI study conducted in Shiraz, Iran, was to study the local epidemiology of HAIs and the major risk factors for acquiring HAIs in a Middle-Eastern region. Methods: The study employed four identical point prevalence surveys in eight university hospitals, each consisting of 60–700 beds. The study was conducted during all four season of 2008–2009. All of the patients admitted for ≥48 h were studied, although the patients admitted to emergency wards were excluded. A standardized data collection form that included name, age, gender, presence or absence of HAI, administration of any antibiotics, insertion of a central line, use of an endotracheal tube, mechanical ventilation, and use of an urinary catheter was completed for each patient. The HAI definitions used in this study were based on the US National Nosocomial Infection Surveillance (NNIS) guidelines. Results: Data from 3450 patients were prospectively collected and analyzed. The overall HAI prevalence was 9.4%. The most common HAIs were blood stream infections (2.5%), surgical site infections (2.4%), urinary tract infections (1.4%), and pneumonia (1.3%). A logistic regression analysis showed that the odds ratio OR for males rather than females acquiring infections was 1.56 (95% confidence interval [CI] 1.21–2.02). Other HAI risk factors included using a central intravascular catheter, adjusted OR of 3.86 (95% CI 2.38–6.26), and using an urinary catheter, adjusted OR of 3.06 (95% CI 2.19–4.28). Being admitted to an ICU was not an independent HAI risk factor. For all HAIs, the OR of acquiring infection was 3.24 (95% CI 2.34–4.47) in the patients with hospital stays longer than eight days. A high discrepancy between HAIs and antibiotic use was observed. Antibiotics were administered to 71% of the patients, but only 9.4% of the patients also had at least one documented infection. Conclusion: This point prevalence study showed that HAIs are frequent in Shiraz university hospitals, and that the proportion of patients receiving antibiotics is high. The results imply that more primary prevention efforts are necessary to address HAIs associated with using indwelling devices and to prevent surgical site infections. Keywords: Hospital acquired infection, Nosocomial infection, Point prevalence, Risk factor, Iran |
| first_indexed | 2024-12-21T19:20:52Z |
| format | Article |
| id | doaj.art-8e16c831588142b8876537e68c00bec6 |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-21T19:20:52Z |
| publishDate | 2012-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-8e16c831588142b8876537e68c00bec62022-12-21T18:52:57ZengElsevierJournal of Infection and Public Health1876-03412012-04-0152169176Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, IranMehrdad Askarian0Mahnaz Yadollahi1Ojan Assadian2Department of Community Medicine, Shiraz Medicinal & Natural Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Corresponding author at: Department of Community Medicine, Shiraz University of Medical Sciences, PO Box 71345-1737, Shiraz, Iran. Tel.: +98 917 1125777; fax: +98 711 2354431.Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, IranClinical Institute for Hospital Hygiene, Medical University of Vienna, AustriaSummary: Background: Hospital-acquired infections (HAIs) are critical and mostly preventable complications that occur in hospitalized patients and lead to major health and economic burdens. Most of the information on HAI risk factors and the recommended preventive measures is based on data acquired from only a few countries. The aim of this point prevalence HAI study conducted in Shiraz, Iran, was to study the local epidemiology of HAIs and the major risk factors for acquiring HAIs in a Middle-Eastern region. Methods: The study employed four identical point prevalence surveys in eight university hospitals, each consisting of 60–700 beds. The study was conducted during all four season of 2008–2009. All of the patients admitted for ≥48 h were studied, although the patients admitted to emergency wards were excluded. A standardized data collection form that included name, age, gender, presence or absence of HAI, administration of any antibiotics, insertion of a central line, use of an endotracheal tube, mechanical ventilation, and use of an urinary catheter was completed for each patient. The HAI definitions used in this study were based on the US National Nosocomial Infection Surveillance (NNIS) guidelines. Results: Data from 3450 patients were prospectively collected and analyzed. The overall HAI prevalence was 9.4%. The most common HAIs were blood stream infections (2.5%), surgical site infections (2.4%), urinary tract infections (1.4%), and pneumonia (1.3%). A logistic regression analysis showed that the odds ratio OR for males rather than females acquiring infections was 1.56 (95% confidence interval [CI] 1.21–2.02). Other HAI risk factors included using a central intravascular catheter, adjusted OR of 3.86 (95% CI 2.38–6.26), and using an urinary catheter, adjusted OR of 3.06 (95% CI 2.19–4.28). Being admitted to an ICU was not an independent HAI risk factor. For all HAIs, the OR of acquiring infection was 3.24 (95% CI 2.34–4.47) in the patients with hospital stays longer than eight days. A high discrepancy between HAIs and antibiotic use was observed. Antibiotics were administered to 71% of the patients, but only 9.4% of the patients also had at least one documented infection. Conclusion: This point prevalence study showed that HAIs are frequent in Shiraz university hospitals, and that the proportion of patients receiving antibiotics is high. The results imply that more primary prevention efforts are necessary to address HAIs associated with using indwelling devices and to prevent surgical site infections. Keywords: Hospital acquired infection, Nosocomial infection, Point prevalence, Risk factor, Iranhttp://www.sciencedirect.com/science/article/pii/S1876034112000081 |
| spellingShingle | Mehrdad Askarian Mahnaz Yadollahi Ojan Assadian Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran Journal of Infection and Public Health |
| title | Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran |
| title_full | Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran |
| title_fullStr | Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran |
| title_full_unstemmed | Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran |
| title_short | Point prevalence and risk factors of hospital acquired infections in a cluster of university-affiliated hospitals in Shiraz, Iran |
| title_sort | point prevalence and risk factors of hospital acquired infections in a cluster of university affiliated hospitals in shiraz iran |
| url | http://www.sciencedirect.com/science/article/pii/S1876034112000081 |
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