Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis
Limbic encephalopathy (LE) is an entity, which may present with memory loss, seizure, psychiatric symptoms and is usually accompanied by neuro-radiology imaging findings. In recent years, antibody tests that can be studied in detail have gained importance as markers. Glutamic acid decarboxylase anti...
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2020-04-01
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| Series: | Archives of Epilepsy |
| Subjects: | |
| Online Access: |
http://archepilepsy.org/archives/archive-detail/article-preview/epileptic-activity-in-a-patient-with-serum-anti-ga/54790
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| _version_ | 1797767406844641280 |
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| author | Zeynep ÖZÖZEN AYAS Dilcan KOTAN |
| author_facet | Zeynep ÖZÖZEN AYAS Dilcan KOTAN |
| author_sort | Zeynep ÖZÖZEN AYAS |
| collection | DOAJ |
| description | Limbic encephalopathy (LE) is an entity, which may present with memory loss, seizure, psychiatric symptoms and is usually accompanied by neuro-radiology imaging findings. In recent years, antibody tests that can be studied in detail have gained importance as markers. Glutamic acid decarboxylase antibody (GAD-Ab) has been reported to be mainly responsible for non-paraneoplastic syndromes. GAD-Ab positivity is predominantly seen in young adult females and temporal lobe epilepsy. Patients with GAD-Ab positive have been reported to respond well or partial to immunotherapy. In this article, we report a 38-year-old woman presenting with seizure and diagnosed with limbic encephalitis who had magnetic resonance imaging and electroencephalograhy findings accompanied by serum GAD-ab positivity was reported. GADAb is considered to play an important role in the prognosis of LE and the other neurological syndromes and should be investigated further. |
| first_indexed | 2024-03-12T20:39:18Z |
| format | Article |
| id | doaj.art-8e1aa76c5e784d7eac498c6cefe74e10 |
| institution | Directory Open Access Journal |
| issn | 2792-0550 |
| language | English |
| last_indexed | 2024-03-12T20:39:18Z |
| publishDate | 2020-04-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Archives of Epilepsy |
| spelling | doaj.art-8e1aa76c5e784d7eac498c6cefe74e102023-08-01T11:13:11ZengGalenos YayineviArchives of Epilepsy2792-05502020-04-01261454810.14744/epilepsi.2019.1687013049054Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic EncephalitisZeynep ÖZÖZEN AYAS0Dilcan KOTAN1 Department of Neurology, Eskişehir City Hospital, Eskişehir Department of Neurology, Sakarya University Faculty of Medicine, Sakarya Limbic encephalopathy (LE) is an entity, which may present with memory loss, seizure, psychiatric symptoms and is usually accompanied by neuro-radiology imaging findings. In recent years, antibody tests that can be studied in detail have gained importance as markers. Glutamic acid decarboxylase antibody (GAD-Ab) has been reported to be mainly responsible for non-paraneoplastic syndromes. GAD-Ab positivity is predominantly seen in young adult females and temporal lobe epilepsy. Patients with GAD-Ab positive have been reported to respond well or partial to immunotherapy. In this article, we report a 38-year-old woman presenting with seizure and diagnosed with limbic encephalitis who had magnetic resonance imaging and electroencephalograhy findings accompanied by serum GAD-ab positivity was reported. GADAb is considered to play an important role in the prognosis of LE and the other neurological syndromes and should be investigated further. http://archepilepsy.org/archives/archive-detail/article-preview/epileptic-activity-in-a-patient-with-serum-anti-ga/54790 anti-gad antibodyepilepsylimbic encephalitis |
| spellingShingle | Zeynep ÖZÖZEN AYAS Dilcan KOTAN Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis Archives of Epilepsy anti-gad antibody epilepsy limbic encephalitis |
| title | Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis |
| title_full | Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis |
| title_fullStr | Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis |
| title_full_unstemmed | Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis |
| title_short | Epileptic Activity in a Patient with Serum Anti-GAD Antibody-positive Limbic Encephalitis |
| title_sort | epileptic activity in a patient with serum anti gad antibody positive limbic encephalitis |
| topic | anti-gad antibody epilepsy limbic encephalitis |
| url |
http://archepilepsy.org/archives/archive-detail/article-preview/epileptic-activity-in-a-patient-with-serum-anti-ga/54790
|
| work_keys_str_mv | AT zeynepozozenayas epilepticactivityinapatientwithserumantigadantibodypositivelimbicencephalitis AT dilcankotan epilepticactivityinapatientwithserumantigadantibodypositivelimbicencephalitis |