Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model.

Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model.

Transforming growth factor-β (TGF-β) has a dual role in tumorigenesis, acting as either a tumor suppressor or as a pro-oncogenic factor in a context-dependent manner. Although TGF-β antagonists have been proposed as anti-metastatic therapies for patients with advanced stage cancer, how TGF-β mediate...

Full description

Bibliographic Details
Main Authors: Misako Sato, Tsutomu Matsubara, Jun Adachi, Yuuki Hashimoto, Kazuna Fukamizu, Marina Kishida, Yu-An Yang, Lalage M Wakefield, Takeshi Tomonaga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4436378?pdf=render

Similar Items

Similar Items