Microwave-assisted synthesis of a series of 4,5-dihydro-1H-pyrazoles endowed with selective COX-1 inhibitory potency

Microwave-assisted synthesis of a series of 4,5-dihydro-1H-pyrazoles endowed with selective COX-1 inhibitory potency

Considerable efforts have been directed towards the discovery of selective cyclooxygenase isoxyme 1 (COX-1) inhibitors due to the recent work highlighting the involvement of COX-1 in the pathogenesis of pain, neuroinflammation, cancer and cardiovascular disorders. In this context, this paper aims to...

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Bibliographic Details
Main Authors:	Altintop Mehlika Dilek, Temel Halide Edip, Özdemir Ahmet
Format:	Article
Language:	English
Published:	Serbian Chemical Society 2023-01-01
Series:	Journal of the Serbian Chemical Society
Subjects:	pyrazoline microwave heating cyclooxygenase-1 inhibition
Online Access:	https://doiserbia.nb.rs/img/doi/0352-5139/2023/0352-51392300001A.pdf

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