Potentially inappropriate medication and attitudes of older adults towards deprescribing.
<h4>Introduction</h4>Multimorbidity and polypharmacy are current challenges when caring for the older population. Both have led to an increase of potentially inappropriate medication (PIM), illustrating the need to assess patients' attitudes towards deprescribing. We aimed to assess...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0240463 |
| _version_ | 1818843642397196288 |
|---|---|
| author | Alexandra B Achterhof Zsofia Rozsnyai Emily Reeve Katharina Tabea Jungo Carmen Floriani Rosalinde K E Poortvliet Nicolas Rodondi Jacobijn Gussekloo Sven Streit |
| author_facet | Alexandra B Achterhof Zsofia Rozsnyai Emily Reeve Katharina Tabea Jungo Carmen Floriani Rosalinde K E Poortvliet Nicolas Rodondi Jacobijn Gussekloo Sven Streit |
| author_sort | Alexandra B Achterhof |
| collection | DOAJ |
| description | <h4>Introduction</h4>Multimorbidity and polypharmacy are current challenges when caring for the older population. Both have led to an increase of potentially inappropriate medication (PIM), illustrating the need to assess patients' attitudes towards deprescribing. We aimed to assess the prevalence of PIM use and whether this was associated with patient factors and willingness to deprescribe.<h4>Method</h4>We analysed data from the LESS Study, a cross-sectional study on self-reported medication and on barriers and enablers towards the willingness to deprescribe (rPATD questionnaire). The survey was conducted among multimorbid (≥3 chronic conditions) participants ≥70 years with polypharmacy (≥5 long-term medications). A subset of the Beers 2019 criteria was applied for the assessment of medication appropriateness.<h4>Results</h4>Data from 300 patients were analysed. The mean age was 79.1 years (SD 5.7). 53% had at least one PIM (men: 47.8%%, women: 60.4%%; p = 0.007). A higher number of medications was associated with PIM use (p = 0.002). We found high willingness to deprescribe in both participants with and without PIM. Willingness to deprescribe was not associated with PIM use (p = 0.25), nor number of PIMs (p = 0.81).<h4>Conclusion</h4>The willingness of older adults with polypharmacy towards deprescribing was not associated with PIM use in this study. These results suggest that patients may not be aware if they are taking PIMs. This implies the need for raising patients' awareness about PIMs through education, especially in females, in order to implement deprescribing in daily practice. |
| first_indexed | 2024-12-19T05:01:07Z |
| format | Article |
| id | doaj.art-8e24ba931793424b87cd179a9ecd1e2d |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-19T05:01:07Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-8e24ba931793424b87cd179a9ecd1e2d2022-12-21T20:35:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011510e024046310.1371/journal.pone.0240463Potentially inappropriate medication and attitudes of older adults towards deprescribing.Alexandra B AchterhofZsofia RozsnyaiEmily ReeveKatharina Tabea JungoCarmen FlorianiRosalinde K E PoortvlietNicolas RodondiJacobijn GusseklooSven Streit<h4>Introduction</h4>Multimorbidity and polypharmacy are current challenges when caring for the older population. Both have led to an increase of potentially inappropriate medication (PIM), illustrating the need to assess patients' attitudes towards deprescribing. We aimed to assess the prevalence of PIM use and whether this was associated with patient factors and willingness to deprescribe.<h4>Method</h4>We analysed data from the LESS Study, a cross-sectional study on self-reported medication and on barriers and enablers towards the willingness to deprescribe (rPATD questionnaire). The survey was conducted among multimorbid (≥3 chronic conditions) participants ≥70 years with polypharmacy (≥5 long-term medications). A subset of the Beers 2019 criteria was applied for the assessment of medication appropriateness.<h4>Results</h4>Data from 300 patients were analysed. The mean age was 79.1 years (SD 5.7). 53% had at least one PIM (men: 47.8%%, women: 60.4%%; p = 0.007). A higher number of medications was associated with PIM use (p = 0.002). We found high willingness to deprescribe in both participants with and without PIM. Willingness to deprescribe was not associated with PIM use (p = 0.25), nor number of PIMs (p = 0.81).<h4>Conclusion</h4>The willingness of older adults with polypharmacy towards deprescribing was not associated with PIM use in this study. These results suggest that patients may not be aware if they are taking PIMs. This implies the need for raising patients' awareness about PIMs through education, especially in females, in order to implement deprescribing in daily practice.https://doi.org/10.1371/journal.pone.0240463 |
| spellingShingle | Alexandra B Achterhof Zsofia Rozsnyai Emily Reeve Katharina Tabea Jungo Carmen Floriani Rosalinde K E Poortvliet Nicolas Rodondi Jacobijn Gussekloo Sven Streit Potentially inappropriate medication and attitudes of older adults towards deprescribing. PLoS ONE |
| title | Potentially inappropriate medication and attitudes of older adults towards deprescribing. |
| title_full | Potentially inappropriate medication and attitudes of older adults towards deprescribing. |
| title_fullStr | Potentially inappropriate medication and attitudes of older adults towards deprescribing. |
| title_full_unstemmed | Potentially inappropriate medication and attitudes of older adults towards deprescribing. |
| title_short | Potentially inappropriate medication and attitudes of older adults towards deprescribing. |
| title_sort | potentially inappropriate medication and attitudes of older adults towards deprescribing |
| url | https://doi.org/10.1371/journal.pone.0240463 |
| work_keys_str_mv | AT alexandrabachterhof potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT zsofiarozsnyai potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT emilyreeve potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT katharinatabeajungo potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT carmenfloriani potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT rosalindekepoortvliet potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT nicolasrodondi potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT jacobijngussekloo potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing AT svenstreit potentiallyinappropriatemedicationandattitudesofolderadultstowardsdeprescribing |