Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction
Abstract Background To observe myocardial deformations in fetuses with isolated lower urinary tract obstruction (LUTO) and identify the correlation between myocardial deformation and the severity of obstruction. Methods The strain (S), strain rate in systole (SRs) and strain rate in diastole (SRd) o...
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | http://link.springer.com/article/10.1186/s12884-020-03152-y |
| _version_ | 1818455571004653568 |
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| author | Ran Xu Jiawei Zhou Qichang Zhou Shi Zeng |
| author_facet | Ran Xu Jiawei Zhou Qichang Zhou Shi Zeng |
| author_sort | Ran Xu |
| collection | DOAJ |
| description | Abstract Background To observe myocardial deformations in fetuses with isolated lower urinary tract obstruction (LUTO) and identify the correlation between myocardial deformation and the severity of obstruction. Methods The strain (S), strain rate in systole (SRs) and strain rate in diastole (SRd) of the left and right ventricles at the first examination were prospectively analyzed and compared between fetuses with isolated LUTO and gestational age (GA)-matched normal control fetuses. Multiple regression analyses were used to assess the obstructive factors for impaired strain and strain rate, and the independent variables included bladder volume, sum of the bilateral pelvic diameters, sum of the bilateral ureteral diameters, mean bilateral renal artery pulsatility index, and amniotic fluid index. Results Thirty-six fetuses with isolated LUTO and 36 normal controls were enrolled. Overall, decreased S, SRs and SRd of both ventricles were noted in fetuses with LUTO (p < 0.001). Moreover, S and SR were significantly negatively related to distended bladder volume (p < 0.001). Conclusions Fetuses with LUTO demonstrated decreased left and right myocardial deformation, and this impaired cardiac dysfunction was correlated with the urinary bladder volume. Evaluating the myocardial deformation in fetal LUTO could provide information to aid in parental counselling and intervention monitoring. |
| first_indexed | 2024-12-14T22:12:53Z |
| format | Article |
| id | doaj.art-8e2693c6f3cc4b35bcc4185bd8c9e25a |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-14T22:12:53Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-8e2693c6f3cc4b35bcc4185bd8c9e25a2022-12-21T22:45:42ZengBMCBMC Pregnancy and Childbirth1471-23932020-08-012011710.1186/s12884-020-03152-yDecreased biventricular myocardial deformation in fetuses with lower urinary tract obstructionRan Xu0Jiawei Zhou1Qichang Zhou2Shi Zeng3Department of Urology, The Second Xiangya Hospital, Central South UniversityDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South UniversityDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South UniversityDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South UniversityAbstract Background To observe myocardial deformations in fetuses with isolated lower urinary tract obstruction (LUTO) and identify the correlation between myocardial deformation and the severity of obstruction. Methods The strain (S), strain rate in systole (SRs) and strain rate in diastole (SRd) of the left and right ventricles at the first examination were prospectively analyzed and compared between fetuses with isolated LUTO and gestational age (GA)-matched normal control fetuses. Multiple regression analyses were used to assess the obstructive factors for impaired strain and strain rate, and the independent variables included bladder volume, sum of the bilateral pelvic diameters, sum of the bilateral ureteral diameters, mean bilateral renal artery pulsatility index, and amniotic fluid index. Results Thirty-six fetuses with isolated LUTO and 36 normal controls were enrolled. Overall, decreased S, SRs and SRd of both ventricles were noted in fetuses with LUTO (p < 0.001). Moreover, S and SR were significantly negatively related to distended bladder volume (p < 0.001). Conclusions Fetuses with LUTO demonstrated decreased left and right myocardial deformation, and this impaired cardiac dysfunction was correlated with the urinary bladder volume. Evaluating the myocardial deformation in fetal LUTO could provide information to aid in parental counselling and intervention monitoring.http://link.springer.com/article/10.1186/s12884-020-03152-ylower urinary tract obstructionmyocardial deformationstrainstrain ratefetus |
| spellingShingle | Ran Xu Jiawei Zhou Qichang Zhou Shi Zeng Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction BMC Pregnancy and Childbirth lower urinary tract obstruction myocardial deformation strain strain rate fetus |
| title | Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction |
| title_full | Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction |
| title_fullStr | Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction |
| title_full_unstemmed | Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction |
| title_short | Decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction |
| title_sort | decreased biventricular myocardial deformation in fetuses with lower urinary tract obstruction |
| topic | lower urinary tract obstruction myocardial deformation strain strain rate fetus |
| url | http://link.springer.com/article/10.1186/s12884-020-03152-y |
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