COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants
About one year after the identification of the first cases of pneumonia due to a novel coronavirus in Wuhan, several vaccines against SARS-CoV-2/COVID-19 started to be approved for emergency use or authorized for early or limited use. The rapid development of effective vaccines based on different te...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/10/6/905 |
| _version_ | 1797481635135881216 |
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| author | Paola Stefanelli Giovanni Rezza |
| author_facet | Paola Stefanelli Giovanni Rezza |
| author_sort | Paola Stefanelli |
| collection | DOAJ |
| description | About one year after the identification of the first cases of pneumonia due to a novel coronavirus in Wuhan, several vaccines against SARS-CoV-2/COVID-19 started to be approved for emergency use or authorized for early or limited use. The rapid development of effective vaccines based on different technological platforms represents an unprecedented success for vaccinology, providing a unique opportunity for a successful public health intervention. However, it is widely known that only a limited number of vaccine doses are usually available at the beginning of vaccination campaigns against an emerging virus; in this phase, protecting health care workers and reducing mortality rates is the priority. When a larger number of vaccines become available, the identification of the drivers of virus circulation coupled with the use of transmission blocking vaccines are key to achieve epidemic control through population immunity. However, as we learned during the vaccination campaigns against the pandemic coronavirus, several factors may hamper this process. Thus, flexible plans are required to obtain the best sustainable result with available tools, modulating vaccination strategies in accordance with improved scientific knowledge, and taking into account the duration of protective immune response, virus evolution, and changing epidemic dynamics. |
| first_indexed | 2024-03-09T22:17:24Z |
| format | Article |
| id | doaj.art-8e28dcedbe9c45d5a97006a3fb8ebb84 |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-09T22:17:24Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-8e28dcedbe9c45d5a97006a3fb8ebb842023-11-23T19:21:12ZengMDPI AGVaccines2076-393X2022-06-0110690510.3390/vaccines10060905COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 VariantsPaola Stefanelli0Giovanni Rezza1Department of Infectious Diseases, Istituto Superiore di Sanità, 00161 Rome, ItalyDirectorate of Health Prevention, Ministry of Health, 00144 Rome, ItalyAbout one year after the identification of the first cases of pneumonia due to a novel coronavirus in Wuhan, several vaccines against SARS-CoV-2/COVID-19 started to be approved for emergency use or authorized for early or limited use. The rapid development of effective vaccines based on different technological platforms represents an unprecedented success for vaccinology, providing a unique opportunity for a successful public health intervention. However, it is widely known that only a limited number of vaccine doses are usually available at the beginning of vaccination campaigns against an emerging virus; in this phase, protecting health care workers and reducing mortality rates is the priority. When a larger number of vaccines become available, the identification of the drivers of virus circulation coupled with the use of transmission blocking vaccines are key to achieve epidemic control through population immunity. However, as we learned during the vaccination campaigns against the pandemic coronavirus, several factors may hamper this process. Thus, flexible plans are required to obtain the best sustainable result with available tools, modulating vaccination strategies in accordance with improved scientific knowledge, and taking into account the duration of protective immune response, virus evolution, and changing epidemic dynamics.https://www.mdpi.com/2076-393X/10/6/905SARS-CoV-2COVID-19vaccinesvaccination strategiesvariants |
| spellingShingle | Paola Stefanelli Giovanni Rezza COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants Vaccines SARS-CoV-2 COVID-19 vaccines vaccination strategies variants |
| title | COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants |
| title_full | COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants |
| title_fullStr | COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants |
| title_full_unstemmed | COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants |
| title_short | COVID-19 Vaccination Strategies and Their Adaptation to the Emergence of SARS-CoV-2 Variants |
| title_sort | covid 19 vaccination strategies and their adaptation to the emergence of sars cov 2 variants |
| topic | SARS-CoV-2 COVID-19 vaccines vaccination strategies variants |
| url | https://www.mdpi.com/2076-393X/10/6/905 |
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