Coeliac disease – systematic review of origin, pathology, diagnosis and treatment
Introduction and Purpose: Coeliac disease is an increasingly prevalent disorder worldwide. It is estimated to affect about 1% of the population and its symptoms heavily impact people's lives. The aim of this paper is to delve into the topic of coeliac disease and present basic information abou...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2023-08-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/44980 |
| _version_ | 1797745060488413184 |
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| author | Krzysztof Puchalski Maciej Zwolski Zuzanna Szumlas Konrad Klocek Aleksandra Hajduk Aleksander Jurek Łukasz Mrozek Bartosz Kostecki |
| author_facet | Krzysztof Puchalski Maciej Zwolski Zuzanna Szumlas Konrad Klocek Aleksandra Hajduk Aleksander Jurek Łukasz Mrozek Bartosz Kostecki |
| author_sort | Krzysztof Puchalski |
| collection | DOAJ |
| description |
Introduction and Purpose: Coeliac disease is an increasingly prevalent disorder worldwide. It is estimated to affect about 1% of the population and its symptoms heavily impact people's lives. The aim of this paper is to delve into the topic of coeliac disease and present basic information about its origins, current diagnostic methods, and the challenges associated with its treatment. This article includes all the necessary information from up-to-date sources.
State of Knowledge: Coeliac disease was discovered a long time ago, but it is still not completely understood. Every year, new research is published regarding different populations in various countries. While we know more about the disease, its symptoms, and causes, we are still far from fully understanding all the inflammatory processes occurring in the human body. There is solid evidence that this enteropathy is caused by gluten, and the only way to reduce the clinical manifestation of coeliac disease is to adhere to a gluten-free diet. However, some patients do not benefit from this type of diet and still suffer from coeliac disease. New drugs currently being developed offer hope for these individuals, as they attempt to target the immunological reaction and mitigate the immune response in the small intestine.
Conclusion: As approximately 1% of the population suffers from this disease, it is crucial to diagnose patients in the early stages of its development. Early diagnosis can prevent the development of other disorders that coexist with coeliac disease, which can be particularly dangerous, especially for children. This paper provides up-to-date information about the clinical manifestations of the disease, as well as methods of diagnosis.
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| first_indexed | 2024-03-12T15:18:06Z |
| format | Article |
| id | doaj.art-8e292107692f4bb1997ed15fb34e17fc |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-12T15:18:06Z |
| publishDate | 2023-08-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-8e292107692f4bb1997ed15fb34e17fc2023-08-11T10:48:01ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0139110.12775/JEHS.2023.39.01.011Coeliac disease – systematic review of origin, pathology, diagnosis and treatmentKrzysztof Puchalski0Maciej Zwolski1Zuzanna Szumlas2Konrad Klocek3Aleksandra Hajduk4Aleksander Jurek5Łukasz Mrozek6Bartosz Kostecki7Samodzielny Publiczny Zespół Zakładów Opieki Zdrowotnej im. Marszałka Józefa Piłsudskiego w Płońsku, 09-100 Płońsk, ul. Henryka Sienkiewicza 7Szpital św. Elżbieta w Katowicach ul. Warszawska 52, 40-008 KatowiceLUX MED Sp. z o.o., ul. Postępu 21C, 02-676 WarszawaGórnośląskie Centrum Medyczne im. prof. Leszka Gieca Śląskiego Uniwersytetu Medycznego w Katowicach, Ziołowa 45-47, 40-635 KatowiceWarszawski Uniwersytet Medyczny, Żwirki i Wigury 61, 02-091 Warszawa UCK WUM Szpital Kliniczny Dzieciątka Jezus, ul. Lindleya 4, 02-005 WarszawaSamodzielny Publiczny Specjalistyczny Szpital Zachodni im. Św. Jana Pawła II, ul. Daleka 11, 05-825 Grodzisk Mazowiecki, Poland SP ZOZ Szpital Wielospecjalistyczny w Jaworznie, Józefa Chełmońskiego 28, 43-600 Jaworzno Introduction and Purpose: Coeliac disease is an increasingly prevalent disorder worldwide. It is estimated to affect about 1% of the population and its symptoms heavily impact people's lives. The aim of this paper is to delve into the topic of coeliac disease and present basic information about its origins, current diagnostic methods, and the challenges associated with its treatment. This article includes all the necessary information from up-to-date sources. State of Knowledge: Coeliac disease was discovered a long time ago, but it is still not completely understood. Every year, new research is published regarding different populations in various countries. While we know more about the disease, its symptoms, and causes, we are still far from fully understanding all the inflammatory processes occurring in the human body. There is solid evidence that this enteropathy is caused by gluten, and the only way to reduce the clinical manifestation of coeliac disease is to adhere to a gluten-free diet. However, some patients do not benefit from this type of diet and still suffer from coeliac disease. New drugs currently being developed offer hope for these individuals, as they attempt to target the immunological reaction and mitigate the immune response in the small intestine. Conclusion: As approximately 1% of the population suffers from this disease, it is crucial to diagnose patients in the early stages of its development. Early diagnosis can prevent the development of other disorders that coexist with coeliac disease, which can be particularly dangerous, especially for children. This paper provides up-to-date information about the clinical manifestations of the disease, as well as methods of diagnosis. https://apcz.umk.pl/JEHS/article/view/44980coeliac diseaseHLA DQ2HLA DQ8glutengluten-freeTG2-abs |
| spellingShingle | Krzysztof Puchalski Maciej Zwolski Zuzanna Szumlas Konrad Klocek Aleksandra Hajduk Aleksander Jurek Łukasz Mrozek Bartosz Kostecki Coeliac disease – systematic review of origin, pathology, diagnosis and treatment Journal of Education, Health and Sport coeliac disease HLA DQ2 HLA DQ8 gluten gluten-free TG2-abs |
| title | Coeliac disease – systematic review of origin, pathology, diagnosis and treatment |
| title_full | Coeliac disease – systematic review of origin, pathology, diagnosis and treatment |
| title_fullStr | Coeliac disease – systematic review of origin, pathology, diagnosis and treatment |
| title_full_unstemmed | Coeliac disease – systematic review of origin, pathology, diagnosis and treatment |
| title_short | Coeliac disease – systematic review of origin, pathology, diagnosis and treatment |
| title_sort | coeliac disease systematic review of origin pathology diagnosis and treatment |
| topic | coeliac disease HLA DQ2 HLA DQ8 gluten gluten-free TG2-abs |
| url | https://apcz.umk.pl/JEHS/article/view/44980 |
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