Jianpi Yangwei decoction promotes apoptosis and suppresses proliferation of 5-fluorouracil resistant gastric cancer cells in vitro and in vivo

Jianpi Yangwei decoction promotes apoptosis and suppresses proliferation of 5-fluorouracil resistant gastric cancer cells in vitro and in vivo

Abstract Background The exploration of new therapeutic agents targeting 5-Fu resistance may open a new opportunity to gastric cancer treatment. The objective is to establish a 5-Fu resistant gastric cancer cell line and observe the effect of Jianpi Yangwei decoction (JPYW) on its apoptosis and drug-...

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Bibliographic Details
Main Authors: Huijuan Tang, Wenjie Huang, Qiang Yang, Ying Lin, Yihui Chen, Peng Shu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Jianpi Yangwei decoction
Gastric cancer
Drug-resistance
PI3K/AKT pathway
Online Access:http://link.springer.com/article/10.1186/s12906-020-03135-8

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