Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile
ABSTRACT The Neuropsychiatric Inventory Questionnaire (NPI-Q) is an informant-based instrument that measures the presence and severity of 12 Neuropsychiatric Symptoms (NPS) in patients with dementia, as well as informant distress. Objective: To measure the psychometric properties of the NPI-Q and t...
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
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| Series: | Dementia & Neuropsychologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000200129&lng=en&tlng=en |
| _version_ | 1828805551691137024 |
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| author | Gada Musa Fernando Henríquez Carlos Muñoz-Neira Carolina Delgado Patricia Lillo Andrea Slachevsky |
| author_facet | Gada Musa Fernando Henríquez Carlos Muñoz-Neira Carolina Delgado Patricia Lillo Andrea Slachevsky |
| author_sort | Gada Musa |
| collection | DOAJ |
| description | ABSTRACT The Neuropsychiatric Inventory Questionnaire (NPI-Q) is an informant-based instrument that measures the presence and severity of 12 Neuropsychiatric Symptoms (NPS) in patients with dementia, as well as informant distress. Objective: To measure the psychometric properties of the NPI-Q and the prevalence of NPS in patients with Alzheimer's disease (AD) in Chile. Methods: 53 patients with AD were assessed. Subjects were divided into two different groups: mild AD (n=26) and moderate AD (n=27). Convergent validity was estimated by correlating the outcomes of the NPI-Q with Neuropsychiatric Inventory (NPI) scores and with a global cognitive efficiency test (Addenbrooke's Cognitive Examination - Revised - ACE-R). Reliability of the NPI-Q was analysed by calculating its internal consistency. Prevalence of NPS was estimated with both the NPI and NPI-Q. Results: Positive and significant correlations were observed between the NPI-Q, the NPI, and the ACE-R (r=0.730; p<0.01 and 0.315; p<0.05 respectively). The instrument displayed an adequate level of reliability (Cronbach's alpha=0.783). The most prevalent NPS were apathy/indifference (62.3%) and dysphoria/depression (58.5%). Conclusion: The NPI-Q exhibited acceptable validity and reliability indicators for patients with AD in Chile, indicating that it is a suitable instrument for the routine assessment of NPS in clinical practice. |
| first_indexed | 2024-12-12T07:56:03Z |
| format | Article |
| id | doaj.art-8e2ac56e15494e0eab31777c266198aa |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-12-12T07:56:03Z |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-8e2ac56e15494e0eab31777c266198aa2022-12-22T00:32:18ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-576411212913610.1590/1980-57642016dn11-020005S1980-57642017000200129Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in ChileGada MusaFernando HenríquezCarlos Muñoz-NeiraCarolina DelgadoPatricia LilloAndrea SlachevskyABSTRACT The Neuropsychiatric Inventory Questionnaire (NPI-Q) is an informant-based instrument that measures the presence and severity of 12 Neuropsychiatric Symptoms (NPS) in patients with dementia, as well as informant distress. Objective: To measure the psychometric properties of the NPI-Q and the prevalence of NPS in patients with Alzheimer's disease (AD) in Chile. Methods: 53 patients with AD were assessed. Subjects were divided into two different groups: mild AD (n=26) and moderate AD (n=27). Convergent validity was estimated by correlating the outcomes of the NPI-Q with Neuropsychiatric Inventory (NPI) scores and with a global cognitive efficiency test (Addenbrooke's Cognitive Examination - Revised - ACE-R). Reliability of the NPI-Q was analysed by calculating its internal consistency. Prevalence of NPS was estimated with both the NPI and NPI-Q. Results: Positive and significant correlations were observed between the NPI-Q, the NPI, and the ACE-R (r=0.730; p<0.01 and 0.315; p<0.05 respectively). The instrument displayed an adequate level of reliability (Cronbach's alpha=0.783). The most prevalent NPS were apathy/indifference (62.3%) and dysphoria/depression (58.5%). Conclusion: The NPI-Q exhibited acceptable validity and reliability indicators for patients with AD in Chile, indicating that it is a suitable instrument for the routine assessment of NPS in clinical practice.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000200129&lng=en&tlng=endemênciaavaliaçãoinventário neuropsiquiátricodoença de Alzheimerprevalênciasintomas neuropsiquiátricos |
| spellingShingle | Gada Musa Fernando Henríquez Carlos Muñoz-Neira Carolina Delgado Patricia Lillo Andrea Slachevsky Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile Dementia & Neuropsychologia demência avaliação inventário neuropsiquiátrico doença de Alzheimer prevalência sintomas neuropsiquiátricos |
| title | Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile |
| title_full | Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile |
| title_fullStr | Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile |
| title_full_unstemmed | Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile |
| title_short | Utility of the Neuropsychiatric Inventory Questionnaire (NPI-Q) in the assessment of a sample of patients with Alzheimer's disease in Chile |
| title_sort | utility of the neuropsychiatric inventory questionnaire npi q in the assessment of a sample of patients with alzheimer s disease in chile |
| topic | demência avaliação inventário neuropsiquiátrico doença de Alzheimer prevalência sintomas neuropsiquiátricos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642017000200129&lng=en&tlng=en |
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