Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins

Tau Oligomers and Fibrils Exhibit Differential Patterns of Seeding and Association With RNA Binding Proteins

Tau aggregates are pleiotropic and exhibit differences in conformation, structure, and size. These aggregates develop endogenously but are also propagated among neurons in disease. We explored the actions of two distinct types of tau aggregates, tau oligomers (oTau) and tau fibrils (fTau), using a s...

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Bibliographic Details
Main Authors: Lulu Jiang, Jian Zhao, Ji-Xin Cheng, Benjamin Wolozin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neurology
Subjects:
tau oligomer
neurofibrillary tangle (NFT)
image proceeding
RNA translation
stress
stress granules
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.579434/full

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