Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride
A straightforward approach for creating fast and novel potentiometric sensors that are modified with multi-walled nanotubes (MWCNTs) was described. The impact of the selective sensor's material was studied. The suggested sensors were successfully fabricated for instant and fast detection of the...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023082051 |
| _version_ | 1797646460485894144 |
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| author | Amal M. Al-Mohaimeed Suliman Y. Al Omar Maha F. El-Tohamy |
| author_facet | Amal M. Al-Mohaimeed Suliman Y. Al Omar Maha F. El-Tohamy |
| author_sort | Amal M. Al-Mohaimeed |
| collection | DOAJ |
| description | A straightforward approach for creating fast and novel potentiometric sensors that are modified with multi-walled nanotubes (MWCNTs) was described. The impact of the selective sensor's material was studied. The suggested sensors were successfully fabricated for instant and fast detection of the prohibited β-adrenoreceptor blocking agent acebutolol hydrochloride (AC) in commercial products. Acebutolol-phosphomolybdate (AC-PM) carbon paste sensor was formed by mixing AC and phosphomolybdic acid and graphite powder in the presence of o-nitrophenyl octyl ether (o-NPOE) as a plasticizing agent. The functionalized AC-PM-MWCNTs and AC-PM-MWCNTs-Al2O3 nanocomposite sensors were prepared and all parameters affecting the sensors' potential responses have been investigated as well as the green synthesis of Al2O3NPs has been characterized using various microscopic and spectroscopic techniques. AC-PM-MWCNTs and AC-PM-MWCNTs-Al2O3 nanocomposite sensors demonstrated linearity of 1.0 × 10−7-1.0 × 10−2 and 1.0 × 10−8-1.0 × 10−2 mol L−1, respectively with regression equations −53.571x + 423.24 (r = 0.999) and −57.107x + 518.54 (r = 0.999). It also revealed excellent selectivity and sensitivity for the determination and quantification of AC. The developed potentiometric system was suitable for the determination of AC in bulk powder and commercial products. |
| first_indexed | 2024-03-11T15:01:54Z |
| format | Article |
| id | doaj.art-8e3120ddd9a549fa8c19871a291473a4 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-11T15:01:54Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-8e3120ddd9a549fa8c19871a291473a42023-10-30T06:08:04ZengElsevierHeliyon2405-84402023-10-01910e20997Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochlorideAmal M. Al-Mohaimeed0Suliman Y. Al Omar1Maha F. El-Tohamy2Department of Chemistry, College of Science, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi ArabiaDoping Research Chair, Zoology Department, College of Science, King Saud University, Riyadh University, Riyadh, 11451, Saudi Arabia; Corresponding author.Department of Chemistry, College of Science, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia; Corresponding author.A straightforward approach for creating fast and novel potentiometric sensors that are modified with multi-walled nanotubes (MWCNTs) was described. The impact of the selective sensor's material was studied. The suggested sensors were successfully fabricated for instant and fast detection of the prohibited β-adrenoreceptor blocking agent acebutolol hydrochloride (AC) in commercial products. Acebutolol-phosphomolybdate (AC-PM) carbon paste sensor was formed by mixing AC and phosphomolybdic acid and graphite powder in the presence of o-nitrophenyl octyl ether (o-NPOE) as a plasticizing agent. The functionalized AC-PM-MWCNTs and AC-PM-MWCNTs-Al2O3 nanocomposite sensors were prepared and all parameters affecting the sensors' potential responses have been investigated as well as the green synthesis of Al2O3NPs has been characterized using various microscopic and spectroscopic techniques. AC-PM-MWCNTs and AC-PM-MWCNTs-Al2O3 nanocomposite sensors demonstrated linearity of 1.0 × 10−7-1.0 × 10−2 and 1.0 × 10−8-1.0 × 10−2 mol L−1, respectively with regression equations −53.571x + 423.24 (r = 0.999) and −57.107x + 518.54 (r = 0.999). It also revealed excellent selectivity and sensitivity for the determination and quantification of AC. The developed potentiometric system was suitable for the determination of AC in bulk powder and commercial products.http://www.sciencedirect.com/science/article/pii/S2405844023082051Abused drugsAcebutolol hydrochlorideMultiwalled carbon nanotubesFunctionalized sensorMetal oxide nanostructuresLavandula spica flowers |
| spellingShingle | Amal M. Al-Mohaimeed Suliman Y. Al Omar Maha F. El-Tohamy Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride Heliyon Abused drugs Acebutolol hydrochloride Multiwalled carbon nanotubes Functionalized sensor Metal oxide nanostructures Lavandula spica flowers |
| title | Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride |
| title_full | Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride |
| title_fullStr | Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride |
| title_full_unstemmed | Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride |
| title_short | Fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride |
| title_sort | fast and novel multiwalled carbon nanotubes decorated with metal oxide nanoparticles for potentiometric detection of a prohibited medication in sports acebutolol hydrochloride |
| topic | Abused drugs Acebutolol hydrochloride Multiwalled carbon nanotubes Functionalized sensor Metal oxide nanostructures Lavandula spica flowers |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023082051 |
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