Drug-Eluting Embolic Loaded with Tyrosine Kinase Inhibitor Targeted Therapies for Transarterial Chemoembolization in a VX2 Model

Drug-Eluting Embolic Loaded with Tyrosine Kinase Inhibitor Targeted Therapies for Transarterial Chemoembolization in a VX2 Model

Drug-eluting embolic transarterial chemoembolization (DEE-TACE) improves the overall survival of hepatocellular carcinoma (HCC), but the agents used are not tailored to HCC. Our patented liposomal formulation enables the loading and elution of targeted therapies onto DEEs. This study aimed to establ...

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Bibliographic Details
Main Authors: Nadine Abi-Jaoudeh, Ben Sadeghi, Hanna Javan, Jim Na, Graham Beaton, Fabio Tucci, Satheesh Ravula, David K. Imagawa
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
transarterial chemoembolization (TACE)
drug-eluting embolics (DEEs)
Sorafenib
Regorafenib
VX2 model
Online Access:https://www.mdpi.com/2072-6694/15/12/3236

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