Structural Comparison of hMDH2 Complexed with Natural Substrates and Cofactors: The Importance of Phosphate Binding for Active Conformation and Catalysis
Malate dehydrogenase (MDH), which catalyzes a reversible conversion of <sub>L</sub>-malate to oxaloacetate, plays essential roles in common metabolic processes, such as the tricarboxylic acid cycle, the oxaloacetate–malate shuttle, and the glyoxylate cycle. MDH2 has lately been recognize...
| Main Authors: | , , |
|---|---|
| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
MDPI AG
2022-08-01
|
| סדרה: | Biomolecules |
| נושאים: | |
| גישה מקוונת: | https://www.mdpi.com/2218-273X/12/9/1175 |