Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group
Introduction: Spinal anaesthesia in the paediatric population is a safe and reliable method of anaesthesia for infraumbilical surgical procedures. As there is greater variation in intrathecal dosing using a conventional weight-based schedule, a prospective cohort study was designed to administer...
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JCDR Research and Publications Private Limited
2020-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/14166/44618_CE[Ra1]_F(SHU)_PF1(Chr_KM)_PFA(Chr_KM)_PN(SL).pdf |
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| author | Parthasarathy Srinivasan Balachandar Saravanan Indu Kulandayan Senthilkumar Thambidura VN Mahalakshmi |
| author_facet | Parthasarathy Srinivasan Balachandar Saravanan Indu Kulandayan Senthilkumar Thambidura VN Mahalakshmi |
| author_sort | Parthasarathy Srinivasan |
| collection | DOAJ |
| description | Introduction: Spinal anaesthesia in the paediatric population
is a safe and reliable method of anaesthesia for infraumbilical
surgical procedures. As there is greater variation in intrathecal
dosing using a conventional weight-based schedule, a
prospective cohort study was designed to administer an agebased intrathecal dosing schedule using 0.5% hyperbaric
bupivacaine for infraumbilical surgeries in paediatric patients.
Aim: To find the efficacy of age-based intrathecal dosing in terms
of level of sensory blockade, success rate and adequacy of
blockade for infraumbilical surgery in the paediatric age group.
Materials and Methods: One hundred and thirty paediatric
patients, aged between 2-12 years, posted for elective
infraumbilical surgeries were given spinal anaesthesia at a dose
of Age/5 (Partha formula) using 0.5% hyperbaric bupivacaine.
Sedation during the procedure was provided using a combination
of effective doses of pentazocine, midazolam, and atropine.
The number of attempts, the success rate, the level of sensory
blockade, the duration of anaesthesia and cardio-respiratory
complications if any were noted.
Results: The mean age of the children was 8±2.55 years. The
mean dose of 0.5% hyperbaric bupivacaine used in this study
was 8±2.55 milligrams. The desired sensory level of T10 was
achieved in the first attempt in all the cases (100%) within
10 minutes of the subarachnoid block. The mean duration of
anaesthesia was 73.42±18.6 minutes. In all the patients, the
surgical procedures were completed within this anaesthetic
time and none of the cases had any conversion to general
anaesthesia. No complications were found in any of the
patients.
Conclusion: Administration of intrathecal dosing of 0.5%
hyperbaric bupivacaine using Partha formula (Age/5) is a safe
and successful method to provide subarachnoid blockade for
infraumbilical surgeries in the Indian paediatric population. |
| first_indexed | 2024-12-21T20:05:48Z |
| format | Article |
| id | doaj.art-8e3da0ae26644f2f9885050830ed25f7 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-21T20:05:48Z |
| publishDate | 2020-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-8e3da0ae26644f2f9885050830ed25f72022-12-21T18:51:51ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-10-011410UC29UC3110.7860/JCDR/2020/44618.14166Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age GroupParthasarathy Srinivasan0Balachandar Saravanan1Indu Kulandayan2Senthilkumar Thambidura3VN Mahalakshmi4Professor, Department of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India.Assistant Professor, Department of Anaesthesiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Karaikal, Puducherry, India.Registrar, Department of Anaesthesiology, Meenakshu Mission Hospital and Research Institute, Madurai, Tamil Nadu, India.Registrar, Department of Anaesthesiology, Meenakshu Mission Hospital and Research Institute, Madurai, Tamil Nadu, India.Dean, HPE, Department of Paediatric Surgery, Aarupadai Veedu Medical College, Puducherry, India.Introduction: Spinal anaesthesia in the paediatric population is a safe and reliable method of anaesthesia for infraumbilical surgical procedures. As there is greater variation in intrathecal dosing using a conventional weight-based schedule, a prospective cohort study was designed to administer an agebased intrathecal dosing schedule using 0.5% hyperbaric bupivacaine for infraumbilical surgeries in paediatric patients. Aim: To find the efficacy of age-based intrathecal dosing in terms of level of sensory blockade, success rate and adequacy of blockade for infraumbilical surgery in the paediatric age group. Materials and Methods: One hundred and thirty paediatric patients, aged between 2-12 years, posted for elective infraumbilical surgeries were given spinal anaesthesia at a dose of Age/5 (Partha formula) using 0.5% hyperbaric bupivacaine. Sedation during the procedure was provided using a combination of effective doses of pentazocine, midazolam, and atropine. The number of attempts, the success rate, the level of sensory blockade, the duration of anaesthesia and cardio-respiratory complications if any were noted. Results: The mean age of the children was 8±2.55 years. The mean dose of 0.5% hyperbaric bupivacaine used in this study was 8±2.55 milligrams. The desired sensory level of T10 was achieved in the first attempt in all the cases (100%) within 10 minutes of the subarachnoid block. The mean duration of anaesthesia was 73.42±18.6 minutes. In all the patients, the surgical procedures were completed within this anaesthetic time and none of the cases had any conversion to general anaesthesia. No complications were found in any of the patients. Conclusion: Administration of intrathecal dosing of 0.5% hyperbaric bupivacaine using Partha formula (Age/5) is a safe and successful method to provide subarachnoid blockade for infraumbilical surgeries in the Indian paediatric population.https://jcdr.net/articles/PDF/14166/44618_CE[Ra1]_F(SHU)_PF1(Chr_KM)_PFA(Chr_KM)_PN(SL).pdfanaesthesiadosagespinal |
| spellingShingle | Parthasarathy Srinivasan Balachandar Saravanan Indu Kulandayan Senthilkumar Thambidura VN Mahalakshmi Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group Journal of Clinical and Diagnostic Research anaesthesia dosage spinal |
| title | Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group |
| title_full | Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group |
| title_fullStr | Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group |
| title_full_unstemmed | Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group |
| title_short | Evaluation of Efficacy and Safety of Age-Based Intrathecal Dosing of 0.5% Hyperbaric Bupivacaine in the Paediatric Age Group |
| title_sort | evaluation of efficacy and safety of age based intrathecal dosing of 0 5 hyperbaric bupivacaine in the paediatric age group |
| topic | anaesthesia dosage spinal |
| url | https://jcdr.net/articles/PDF/14166/44618_CE[Ra1]_F(SHU)_PF1(Chr_KM)_PFA(Chr_KM)_PN(SL).pdf |
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