Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size

The objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second...

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Main Authors: M. A. Aralova, A. A. Glukhov
Format: Article
Language:Russian
Published: Pavlov First Saint Petersburg State Medical University 2019-02-01
Series:Вестник хирургии имени И.И. Грекова
Subjects:
Online Access:https://www.vestnik-grekova.ru/jour/article/view/1192
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author M. A. Aralova
A. A. Glukhov
author_facet M. A. Aralova
A. A. Glukhov
author_sort M. A. Aralova
collection DOAJ
description The objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second 2 phase of wound process. Patients were randomly divided into the main group and 3 control groups.Results. The activation of regeneration processes using a combination of platelet-rich donor plasma and native unreconstructed collagen before autodermoplasty leads to improving the viability and engraftment of transplant, progressive decreasing the area of the wound defect.Conclusion. The use of a combination of donor thromboconcentrate and collagen preparations statistically significantly improves the results of skin transplantation.
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spelling doaj.art-8e4254cd5a0d4e2dba67b0627f7b42e72024-11-26T10:43:53ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252019-02-011781596210.24884/0042-4625-2019-178-1-59-62990Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large sizeM. A. Aralova0A. A. Glukhov1Voronezh State Medical University named after N. N. BurdenkoVoronezh State Medical University named after N. N. BurdenkoThe objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second 2 phase of wound process. Patients were randomly divided into the main group and 3 control groups.Results. The activation of regeneration processes using a combination of platelet-rich donor plasma and native unreconstructed collagen before autodermoplasty leads to improving the viability and engraftment of transplant, progressive decreasing the area of the wound defect.Conclusion. The use of a combination of donor thromboconcentrate and collagen preparations statistically significantly improves the results of skin transplantation.https://www.vestnik-grekova.ru/jour/article/view/1192extensive trophic ulcersthromboconcentratecollagen
spellingShingle M. A. Aralova
A. A. Glukhov
Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
Вестник хирургии имени И.И. Грекова
extensive trophic ulcers
thromboconcentrate
collagen
title Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
title_full Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
title_fullStr Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
title_full_unstemmed Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
title_short Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
title_sort concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
topic extensive trophic ulcers
thromboconcentrate
collagen
url https://www.vestnik-grekova.ru/jour/article/view/1192
work_keys_str_mv AT maaralova concentratedsuspensionofplateletsandcollageninthetreatmentofvenoustrophiculcersoflargesize
AT aaglukhov concentratedsuspensionofplateletsandcollageninthetreatmentofvenoustrophiculcersoflargesize