Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
The objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second...
Main Authors: | , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
Pavlov First Saint Petersburg State Medical University
2019-02-01
|
Series: | Вестник хирургии имени И.И. Грекова |
Subjects: | |
Online Access: | https://www.vestnik-grekova.ru/jour/article/view/1192 |
_version_ | 1826962557548625920 |
---|---|
author | M. A. Aralova A. A. Glukhov |
author_facet | M. A. Aralova A. A. Glukhov |
author_sort | M. A. Aralova |
collection | DOAJ |
description | The objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second 2 phase of wound process. Patients were randomly divided into the main group and 3 control groups.Results. The activation of regeneration processes using a combination of platelet-rich donor plasma and native unreconstructed collagen before autodermoplasty leads to improving the viability and engraftment of transplant, progressive decreasing the area of the wound defect.Conclusion. The use of a combination of donor thromboconcentrate and collagen preparations statistically significantly improves the results of skin transplantation. |
first_indexed | 2024-04-10T02:20:48Z |
format | Article |
id | doaj.art-8e4254cd5a0d4e2dba67b0627f7b42e7 |
institution | Directory Open Access Journal |
issn | 0042-4625 |
language | Russian |
last_indexed | 2025-02-18T02:17:01Z |
publishDate | 2019-02-01 |
publisher | Pavlov First Saint Petersburg State Medical University |
record_format | Article |
series | Вестник хирургии имени И.И. Грекова |
spelling | doaj.art-8e4254cd5a0d4e2dba67b0627f7b42e72024-11-26T10:43:53ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252019-02-011781596210.24884/0042-4625-2019-178-1-59-62990Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large sizeM. A. Aralova0A. A. Glukhov1Voronezh State Medical University named after N. N. BurdenkoVoronezh State Medical University named after N. N. BurdenkoThe objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second 2 phase of wound process. Patients were randomly divided into the main group and 3 control groups.Results. The activation of regeneration processes using a combination of platelet-rich donor plasma and native unreconstructed collagen before autodermoplasty leads to improving the viability and engraftment of transplant, progressive decreasing the area of the wound defect.Conclusion. The use of a combination of donor thromboconcentrate and collagen preparations statistically significantly improves the results of skin transplantation.https://www.vestnik-grekova.ru/jour/article/view/1192extensive trophic ulcersthromboconcentratecollagen |
spellingShingle | M. A. Aralova A. A. Glukhov Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size Вестник хирургии имени И.И. Грекова extensive trophic ulcers thromboconcentrate collagen |
title | Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size |
title_full | Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size |
title_fullStr | Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size |
title_full_unstemmed | Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size |
title_short | Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size |
title_sort | concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size |
topic | extensive trophic ulcers thromboconcentrate collagen |
url | https://www.vestnik-grekova.ru/jour/article/view/1192 |
work_keys_str_mv | AT maaralova concentratedsuspensionofplateletsandcollageninthetreatmentofvenoustrophiculcersoflargesize AT aaglukhov concentratedsuspensionofplateletsandcollageninthetreatmentofvenoustrophiculcersoflargesize |