Protective Roles of Interferon‐γ in Cardiac Hypertrophy Induced by Sustained Pressure Overload

Protective Roles of Interferon‐γ in Cardiac Hypertrophy Induced by Sustained Pressure Overload

BackgroundA clear understanding of the molecular mechanisms underlying hemodynamic stress‐initiated cardiac hypertrophy is important for preventing heart failure. Interferon‐γ (IFN‐γ) has been suggested to play crucial roles in various diseases other than immunological disorders by modulating the ex...

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Bibliographic Details
Main Authors: Akihiko Kimura, Yuko Ishida, Machi Furuta, Mizuho Nosaka, Yumi Kuninaka, Akira Taruya, Naofumi Mukaida, Toshikazu Kondo
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cell signaling
cytokine
hypertrophy
interferon‐γ
PI3K/Akt
protein kinase B
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008145

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