Human Genetic Susceptibility to Native Valve Staphylococcus aureus Endocarditis in Patients With S. aureus Bacteremia: Genome-Wide Association Study

Human Genetic Susceptibility to Native Valve Staphylococcus aureus Endocarditis in Patients With S. aureus Bacteremia: Genome-Wide Association Study

Staphylococcus aureus infective endocarditis (SaIE) is a severe complication of S. aureus bacteremia (SAB) occurring in up to 22% of patients. Bacterial genetic factors and host conditions for SaIE have been intensely studied before; however, to date no study has focused on predisposing host genetic...

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Bibliographic Details
Main Authors: Karen Moreau, Alisson Clemenceau, Vincent Le Moing, David Messika-Zeitoun, Paal S. Andersen, Niels E. Bruun, Robert L. Skov, Florence Couzon, Coralie Bouchiat, Marie L. Erpelding, Alex van Belkum, Yohan Bossé, Xavier Duval, Francois Vandenesch, The French VIRSTA-AEPEI, COFRASA Study Groups, The Danish DANSAB Study Group
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Microbiology
Subjects:
infectious endocarditis
Staphylococcus aureus
GWAS
bacteremia
SLC7A14
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00640/full

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