Induced neuronal activity does not attenuate amyloid beta‐induced synaptic loss in vitro

Abstract Aim The accumulation of amyloid beta (Aβ) is one of the characteristics of Alzheimer's disease. The excessive accumulation of Aβ has been suggested to result in a decrease in the number of synapses. Although the number of synapses is generally modulated by neuronal activity, whether ne...

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Bibliographic Details
Main Authors: Rena Kono, Gyu Li Kim, Hidetaka Nagata, Yuji Ikegaya, Ryuta Koyama
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Neuropsychopharmacology Reports
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Online Access:https://doi.org/10.1002/npr2.12074

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