Reduced number and morphofunctional change of alveolar macrophages in MafB gene-targeted mice.

Reduced number and morphofunctional change of alveolar macrophages in MafB gene-targeted mice.

Alveolar macrophages (AMs) play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). We previously demonstrated that the transcription factor, MafB, increased in the AMs of mice exposed to cigarette smoke, and in those of human patients with COPD. The aim of this st...

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Main Authors: Michiko Sato-Nishiwaki, Yasuko Aida, Shuichi Abe, Yoko Shibata, Tomomi Kimura, Keiko Yamauchi, Hiroyuki Kishi, Akira Igarashi, Sumito Inoue, Masamichi Sato, Osamu Nakajima, Isao Kubota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765310?pdf=render

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