Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions
Background and purpose: Breast cancer is the common cancer in women and the major cause of death due to malignancy in women aged 40-44 years old. The routine method for diagnosis of biopsy specimens is pathologic procedure. Expert pathologists could accurately diagnose malignant and benign diseases...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2019-02-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-11106-en.html |
| _version_ | 1828054951550517248 |
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| author | Esmaeil Sadeghi Mohammad Jafari |
| author_facet | Esmaeil Sadeghi Mohammad Jafari |
| author_sort | Esmaeil Sadeghi |
| collection | DOAJ |
| description | Background and purpose: Breast cancer is the common cancer in women and the major cause of death due to malignancy in women aged 40-44 years old. The routine method for diagnosis of biopsy specimens is pathologic procedure. Expert pathologists could accurately diagnose malignant and benign diseases using cytology methods. The aim of this study was to investigate the sensitivity and specificity of touch preparation cytology compared with pathology in diagnosis of breast lesions.
Materials and methods: In this descriptive cross-sectional study we evaluated patients that had breast operation in Hamadan Bouali Hospital, 2016-2017 by analyzing pathologic recorded reports.
Results: Totally 121 patients were studied including 114 (94.2%) females and 7 (5.8%) males. The mean age of the patients was 40.7 years (15-74 years). Malignant and benign diseases were observed in 61 and 60 patients, respectively. Sensitivity and specificity of touch preparation cytology were 91.8% and 95%, respectively. Positive predictive value and negative predictive value were 94.91% and 91.93%, respectively.
Conclusion: Touch preparation cytology is an accurate and valid method for detecting benign breast lesions and is suggested to be used alongside frozen section to increase sensitivity and specificity of diagnosis. |
| first_indexed | 2024-04-10T20:30:53Z |
| format | Article |
| id | doaj.art-8e561dbc249f43848a966c8d135ada8a |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:30:53Z |
| publishDate | 2019-02-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-8e561dbc249f43848a966c8d135ada8a2023-01-25T06:58:45ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792019-02-0128169108117Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast LesionsEsmaeil Sadeghi0Mohammad Jafari1 Student in Medicine, Student Research Committee, School of Medicine, Hamadan University of Medical Sciences, Hmadan, Iran Associate Professor, Department of Pathology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Background and purpose: Breast cancer is the common cancer in women and the major cause of death due to malignancy in women aged 40-44 years old. The routine method for diagnosis of biopsy specimens is pathologic procedure. Expert pathologists could accurately diagnose malignant and benign diseases using cytology methods. The aim of this study was to investigate the sensitivity and specificity of touch preparation cytology compared with pathology in diagnosis of breast lesions. Materials and methods: In this descriptive cross-sectional study we evaluated patients that had breast operation in Hamadan Bouali Hospital, 2016-2017 by analyzing pathologic recorded reports. Results: Totally 121 patients were studied including 114 (94.2%) females and 7 (5.8%) males. The mean age of the patients was 40.7 years (15-74 years). Malignant and benign diseases were observed in 61 and 60 patients, respectively. Sensitivity and specificity of touch preparation cytology were 91.8% and 95%, respectively. Positive predictive value and negative predictive value were 94.91% and 91.93%, respectively. Conclusion: Touch preparation cytology is an accurate and valid method for detecting benign breast lesions and is suggested to be used alongside frozen section to increase sensitivity and specificity of diagnosis.http://jmums.mazums.ac.ir/article-1-11106-en.htmltouch preparation cytologypathologybreast lesionsensitivityspecificity |
| spellingShingle | Esmaeil Sadeghi Mohammad Jafari Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions Journal of Mazandaran University of Medical Sciences touch preparation cytology pathology breast lesion sensitivity specificity |
| title | Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions |
| title_full | Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions |
| title_fullStr | Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions |
| title_full_unstemmed | Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions |
| title_short | Comparing the Sensitivity and Specificity of Touch Preparation Cytology and Pathology in Diagnose of Breast Lesions |
| title_sort | comparing the sensitivity and specificity of touch preparation cytology and pathology in diagnose of breast lesions |
| topic | touch preparation cytology pathology breast lesion sensitivity specificity |
| url | http://jmums.mazums.ac.ir/article-1-11106-en.html |
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