Harnessing type I interferon-mediated immunity to target malignant brain tumors

Harnessing type I interferon-mediated immunity to target malignant brain tumors

Type I interferons have long been appreciated as a cytokine family that regulates antiviral immunity. Recently, their role in eliciting antitumor immune responses has gained increasing attention. Within the immunosuppressive tumor microenvironment (TME), interferons stimulate tumor-infiltrating lymp...

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Bibliographic Details
Main Authors: Juhee Lim, In Kang, Jeongwoo La, Keun Bon Ku, Byeong Hoon Kang, Yumin Kim, Won Hyung Park, Heung Kyu Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
type I interferons
brain tumors
glioblastoma
tumor microenvironment
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1203929/full

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