Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018
The purpose of this study was to investigate annual changes in BoRVA strains by examining the VP4 and VP7 genes of rotaviruses in Korean calves. Between 2014 and 2018, 35 out of 138 samples of calf diarrhea feces collected nationwide were positive for BoRVA. Further genetic characterization of the V...
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| Format: | Article |
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MDPI AG
2022-12-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/24/3555 |
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| author | Gyu-Nam Park SeEun Choe Ra Mi Cha Jihye Shin Ki-Sun Kim Byung-Hyun An Song-Yi Kim Bang-Hun Hyun Dong-Jun An |
| author_facet | Gyu-Nam Park SeEun Choe Ra Mi Cha Jihye Shin Ki-Sun Kim Byung-Hyun An Song-Yi Kim Bang-Hun Hyun Dong-Jun An |
| author_sort | Gyu-Nam Park |
| collection | DOAJ |
| description | The purpose of this study was to investigate annual changes in BoRVA strains by examining the VP4 and VP7 genes of rotaviruses in Korean calves. Between 2014 and 2018, 35 out of 138 samples of calf diarrhea feces collected nationwide were positive for BoRVA. Further genetic characterization of the VP7 and VP4 genes of 35 BoRVA isolates identified three different G-genotypes (G6, G8, and G10) and two different P genotypes (P[5] and P[11]). The G6 genotype was most common (94.3%) in BoRVA-positive calves, followed by the P[5] genotype (82.9%). Four genotypes comprised combinations of VP4 and VP7: 80% were G6P[5], 14.2% were G6P[11], 2.9% were G8P[5], and 2.9% were G10P[11]. Susceptibility to infection was highest in calves aged < 10 days (35%) and lowest in calves aged 30–50 days (15.4%). The data presented herein suggest that the G6P[5] genotype is the main causative agent of diarrhea in Korean calves. In addition, it is predicted that G6P[5] will continue to act as a major cause of diarrhea in Korean calves. |
| first_indexed | 2024-03-09T17:25:05Z |
| format | Article |
| id | doaj.art-8e5a576a9cfd4a71bb7305aa09cefcad |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T17:25:05Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-8e5a576a9cfd4a71bb7305aa09cefcad2023-11-24T12:51:48ZengMDPI AGAnimals2076-26152022-12-011224355510.3390/ani12243555Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018Gyu-Nam Park0SeEun Choe1Ra Mi Cha2Jihye Shin3Ki-Sun Kim4Byung-Hyun An5Song-Yi Kim6Bang-Hun Hyun7Dong-Jun An8Virus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaDepartment of Veterinary Medicine Virology Laboratory, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, GwanAk-Ro 1, GwanAk-Gu, Seoul 08826, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaVirus Disease Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of KoreaThe purpose of this study was to investigate annual changes in BoRVA strains by examining the VP4 and VP7 genes of rotaviruses in Korean calves. Between 2014 and 2018, 35 out of 138 samples of calf diarrhea feces collected nationwide were positive for BoRVA. Further genetic characterization of the VP7 and VP4 genes of 35 BoRVA isolates identified three different G-genotypes (G6, G8, and G10) and two different P genotypes (P[5] and P[11]). The G6 genotype was most common (94.3%) in BoRVA-positive calves, followed by the P[5] genotype (82.9%). Four genotypes comprised combinations of VP4 and VP7: 80% were G6P[5], 14.2% were G6P[11], 2.9% were G8P[5], and 2.9% were G10P[11]. Susceptibility to infection was highest in calves aged < 10 days (35%) and lowest in calves aged 30–50 days (15.4%). The data presented herein suggest that the G6P[5] genotype is the main causative agent of diarrhea in Korean calves. In addition, it is predicted that G6P[5] will continue to act as a major cause of diarrhea in Korean calves.https://www.mdpi.com/2076-2615/12/24/3555BoRVAphylogenetic treecalfdiarrheagenotype |
| spellingShingle | Gyu-Nam Park SeEun Choe Ra Mi Cha Jihye Shin Ki-Sun Kim Byung-Hyun An Song-Yi Kim Bang-Hun Hyun Dong-Jun An Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018 Animals BoRVA phylogenetic tree calf diarrhea genotype |
| title | Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018 |
| title_full | Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018 |
| title_fullStr | Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018 |
| title_full_unstemmed | Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018 |
| title_short | Genetic Diversity of Bovine Group A Rotavirus Strains Circulating in Korean Calves during 2014 and 2018 |
| title_sort | genetic diversity of bovine group a rotavirus strains circulating in korean calves during 2014 and 2018 |
| topic | BoRVA phylogenetic tree calf diarrhea genotype |
| url | https://www.mdpi.com/2076-2615/12/24/3555 |
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