A Probiotic <i>Lactobacillus gasseri</i> Alleviates <i>Escherichia coli</i>-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota

A Probiotic <i>Lactobacillus gasseri</i> Alleviates <i>Escherichia coli</i>-Induced Cognitive Impairment and Depression in Mice by Regulating IL-1β Expression and Gut Microbiota

Excessive expression of interleukin (IL)-1β in the brain causes depression and cognitive dysfunction. Herein, we investigated the effect of <i>Lactobacillus gasseri</i> NK109, which suppressed IL-1β expression in activated macrophages, on <i>Escherichia coli</i> K1-induced co...

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Bibliographic Details
Main Authors: Soo-Won Yun, Jeon-Kyung Kim, Kyung-Eon Lee, Young Joon Oh, Hak-Jong Choi, Myung Joo Han, Dong-Hyun Kim
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Nutrients
Subjects:
<i>Lactobacillus gasseri</i>
cognition impairment
depression
IL-1β
gut microbiota
Online Access:https://www.mdpi.com/2072-6643/12/11/3441

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