Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis
Patients suffering from multiple sclerosis experience various cognitive and affective impairments, resulting in a negative impact on social behavior and personal independence to differing degrees. According to these often clinically subtle but conflicting cognitive-affective impairments, recordin...
| প্রধান লেখক: | , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
IMR Press
2022-01-01
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| মালা: | Journal of Integrative Neuroscience |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://article.imrpress.com/journal/JIN/21/1/10.31083/j.jin2101007/1757-448X-21-1-007.pdf |
| _version_ | 1828393724939337728 |
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| author | Michael Adamaszek Stefan Krüger Christof Kessler Norbert Hosten Alfons Hamm |
| author_facet | Michael Adamaszek Stefan Krüger Christof Kessler Norbert Hosten Alfons Hamm |
| author_sort | Michael Adamaszek |
| collection | DOAJ |
| description | Patients suffering from multiple sclerosis experience various cognitive and
affective impairments, resulting in a negative impact on social behavior and
personal independence to differing degrees. According to these often clinically
subtle but conflicting cognitive-affective impairments, recordings of these
socially relevant issues are still of demand to stratifying clinical and social
support in a sophisticated way. Therefore, we studied specific cognitive and
affective capacities in eleven patients with a predominant relapsing-remitting
type of multiple sclerosis by applying paradigms of event-related potentials and
a well-selected neuropsychological test protocol. Thus far, distinct cognitive
disturbances of executive and attentional domains and the Wechsler Memory Test’s
four memory indices were found in multiple sclerosis patients. Concerning
affective domains, patients showed discrete impairments of affect discrimination
and affected naming as proved by specific testing (Tuebinger Affect Battery).
Neurophysiologically, event-related potentials recordings in multiple sclerosis
patients, were associated with decreased implicit emotion processing to cues of
different emotion arousal at the early processing stage depending on attentional
capacities and alterations of implicit emotion modulation at late processing
stages. These clinical neurophysiological and neuropsychological data were
correlated in part to quantitative magnetic resonance imaging brain lesions.
Summarizing our data, our data indicate certain neurocognitive and neuroaffective
dysfunctions in patients with multiple sclerosis, thus highlighting the validity
of sensitive recording of less apparent neurologic disturbances in multiple
sclerosis for optimizing the individual care management in patients. |
| first_indexed | 2024-12-10T07:43:31Z |
| format | Article |
| id | doaj.art-8e5db5bee10e4090839060d6719c3f83 |
| institution | Directory Open Access Journal |
| issn | 0219-6352 |
| language | English |
| last_indexed | 2024-12-10T07:43:31Z |
| publishDate | 2022-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Journal of Integrative Neuroscience |
| spelling | doaj.art-8e5db5bee10e4090839060d6719c3f832022-12-22T01:57:14ZengIMR PressJournal of Integrative Neuroscience0219-63522022-01-0121100710.31083/j.jin2101007S0219-6352(22)00267-4Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosisMichael Adamaszek0Stefan Krüger1Christof Kessler2Norbert Hosten3Alfons Hamm4Department of Clinical and Cognitive Neurorehabilitation, 93413 Klinik Bavaria Kreischa, GermanyAmbulance of Psychotherapy, 14547 Beelitz, GermanyDepartment of Neurology, University of Greifswald, 17489 Greifswald, Mecklenburg-Vorpommern, GermanyDepartment of Diagnostic Radiology and Neuroradiology, University of Greifswald, 17489 Greifswald, Mecklenburg-Vorpommern, GermanyInstitute of Physiological and Clinical Psychology, University of Greifswald, 17489 Greifswald, Mecklenburg-Vorpommern, GermanyPatients suffering from multiple sclerosis experience various cognitive and affective impairments, resulting in a negative impact on social behavior and personal independence to differing degrees. According to these often clinically subtle but conflicting cognitive-affective impairments, recordings of these socially relevant issues are still of demand to stratifying clinical and social support in a sophisticated way. Therefore, we studied specific cognitive and affective capacities in eleven patients with a predominant relapsing-remitting type of multiple sclerosis by applying paradigms of event-related potentials and a well-selected neuropsychological test protocol. Thus far, distinct cognitive disturbances of executive and attentional domains and the Wechsler Memory Test’s four memory indices were found in multiple sclerosis patients. Concerning affective domains, patients showed discrete impairments of affect discrimination and affected naming as proved by specific testing (Tuebinger Affect Battery). Neurophysiologically, event-related potentials recordings in multiple sclerosis patients, were associated with decreased implicit emotion processing to cues of different emotion arousal at the early processing stage depending on attentional capacities and alterations of implicit emotion modulation at late processing stages. These clinical neurophysiological and neuropsychological data were correlated in part to quantitative magnetic resonance imaging brain lesions. Summarizing our data, our data indicate certain neurocognitive and neuroaffective dysfunctions in patients with multiple sclerosis, thus highlighting the validity of sensitive recording of less apparent neurologic disturbances in multiple sclerosis for optimizing the individual care management in patients.https://article.imrpress.com/journal/JIN/21/1/10.31083/j.jin2101007/1757-448X-21-1-007.pdfmultiple sclerosisemotion attentionemotion empathyevent-related potentials |
| spellingShingle | Michael Adamaszek Stefan Krüger Christof Kessler Norbert Hosten Alfons Hamm Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis Journal of Integrative Neuroscience multiple sclerosis emotion attention emotion empathy event-related potentials |
| title | Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis |
| title_full | Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis |
| title_fullStr | Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis |
| title_full_unstemmed | Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis |
| title_short | Clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis |
| title_sort | clinical and neurophysiological patterns of impairments to emotion attention and empathy in multiple sclerosis |
| topic | multiple sclerosis emotion attention emotion empathy event-related potentials |
| url | https://article.imrpress.com/journal/JIN/21/1/10.31083/j.jin2101007/1757-448X-21-1-007.pdf |
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