Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case
Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms. These are aggressive tumors and are commonly associated with conventional (clear cell) renal cell carcinomas, but cases associated with chromophobe renal cell carci...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Journal of Cytology |
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| Online Access: | http://www.jcytol.org/article.asp?issn=0970-9371;year=2010;volume=27;issue=1;spage=29;epage=31;aulast=Chakrabarti |
| _version_ | 1828749896865284096 |
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| author | Chakrabarti Indranil Giri Amita Majumdar Kaushik De Anuradha |
| author_facet | Chakrabarti Indranil Giri Amita Majumdar Kaushik De Anuradha |
| author_sort | Chakrabarti Indranil |
| collection | DOAJ |
| description | Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms. These are aggressive tumors and are commonly associated with conventional (clear cell) renal cell carcinomas, but cases associated with chromophobe renal cell carcinomas are sparse. Cytological features of such lesions have rarely been reported. Here, we report a unique case of a 48-year-old male patient who presented with right flank lump and pain. A fine needle aspiration was performed from the lesion under ultrasound guidance and a cytological diagnosis of pleomorphic sarcoma was made. A right-sided radical nephrectomy was carried out and subsequent histopathology revealed a sarcomatoid renal cell carcinoma with wide areas of necrosis coexisting with chromophobe renal cell carcinoma with calcification. Differentiation of pleomorphic sarcoma from a sarcomatoid renal cell carcinoma is, thus, challenging from cytopathology smears and the differential diagnoses should always be borne in mind while giving a cytopathological opinion. |
| first_indexed | 2024-12-10T20:30:08Z |
| format | Article |
| id | doaj.art-8e5f8603a68548a3b8055bac05e7c04c |
| institution | Directory Open Access Journal |
| issn | 0970-9371 0974-5165 |
| language | English |
| last_indexed | 2024-12-10T20:30:08Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cytology |
| spelling | doaj.art-8e5f8603a68548a3b8055bac05e7c04c2022-12-22T01:34:43ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93710974-51652010-01-012712931Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a caseChakrabarti IndranilGiri AmitaMajumdar KaushikDe AnuradhaSarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms. These are aggressive tumors and are commonly associated with conventional (clear cell) renal cell carcinomas, but cases associated with chromophobe renal cell carcinomas are sparse. Cytological features of such lesions have rarely been reported. Here, we report a unique case of a 48-year-old male patient who presented with right flank lump and pain. A fine needle aspiration was performed from the lesion under ultrasound guidance and a cytological diagnosis of pleomorphic sarcoma was made. A right-sided radical nephrectomy was carried out and subsequent histopathology revealed a sarcomatoid renal cell carcinoma with wide areas of necrosis coexisting with chromophobe renal cell carcinoma with calcification. Differentiation of pleomorphic sarcoma from a sarcomatoid renal cell carcinoma is, thus, challenging from cytopathology smears and the differential diagnoses should always be borne in mind while giving a cytopathological opinion.http://www.jcytol.org/article.asp?issn=0970-9371;year=2010;volume=27;issue=1;spage=29;epage=31;aulast=ChakrabartiCytology; kidney; pleomorphic sarcoma; sarcomatoid chromophobe renal cell carcinoma |
| spellingShingle | Chakrabarti Indranil Giri Amita Majumdar Kaushik De Anuradha Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case Journal of Cytology Cytology; kidney; pleomorphic sarcoma; sarcomatoid chromophobe renal cell carcinoma |
| title | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
| title_full | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
| title_fullStr | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
| title_full_unstemmed | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
| title_short | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
| title_sort | sarcomatoid chromophobe renal cell carcinoma cytohistopathological correlation of a case |
| topic | Cytology; kidney; pleomorphic sarcoma; sarcomatoid chromophobe renal cell carcinoma |
| url | http://www.jcytol.org/article.asp?issn=0970-9371;year=2010;volume=27;issue=1;spage=29;epage=31;aulast=Chakrabarti |
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