Development and evaluation of ofloxacin orally disintegrating tablets

Development and evaluation of ofloxacin orally disintegrating tablets

Bitter taste of ofloxacin, a broad spectrum bactericidal agent, is masked and orally disintegrating tablets were formulated. The bitter taste is masked by forming complex between drug and weak cation exchange resins, Tulsion 335 and Indion 204. Effect of pH and drug:resin ratio on the drug loading w...

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Bibliographic Details
Main Authors: Badrinath Pralhadrao Mohite, Sandip Annaji Chafle, Jayaprakash Somasundaram, Jasmine Gev Avari
Format: Article
Language:English
Published: Universidade de São Paulo 2012-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Tempo de dispersão
Indion 204
Resina de troca iônica
Ofloxacina
Comprimidos de desintegração oral
Comprimidos/desenvolvimento/propriedades
Tulsion 335
Dispersion time
Ion exchange resin
Ofloxacin
Orally disintegrating tablets
Tableting properties
Wetting time
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000200005

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