A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery
Purpose: Fibrin glue and polyglycolic acid felt are used for tissue repair in various surgical procedures. However, using a spray device to apply fibrin sealant during laparoscopic surgery can increase the intraperitoneal pressure, which can cause complications such as air embolism. We developed a n...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-04-01
|
| Series: | Journal of Investigative Surgery |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/08941939.2018.1519050 |
| _version_ | 1797684682294296576 |
|---|---|
| author | Norifumi Tsutsumi Yoshihisa Sakaguchi Tetsuya Kusumoto Koji Ikejiri Ryosuke Tsutsumi Koichi Kimura Soichiro Maekawa |
| author_facet | Norifumi Tsutsumi Yoshihisa Sakaguchi Tetsuya Kusumoto Koji Ikejiri Ryosuke Tsutsumi Koichi Kimura Soichiro Maekawa |
| author_sort | Norifumi Tsutsumi |
| collection | DOAJ |
| description | Purpose: Fibrin glue and polyglycolic acid felt are used for tissue repair in various surgical procedures. However, using a spray device to apply fibrin sealant during laparoscopic surgery can increase the intraperitoneal pressure, which can cause complications such as air embolism. We developed a novel non-gas endospray for use in laparoscopic surgery. This study aimed to evaluate the sealing effect of this non-gas endospray in comparison with a conventional gas-spray device and to evaluate the safety of its application in the clinical setting. Materials and Methods: An ex vivo pressure test model was used to assess the sealing effect of the non-gas endospray (method 1) versus conventional gas-spray (method 2). A bottle was sealed with a rabbit skin sample that had been pierced nine times by a 19G needle. Each skin sample was sealed using either method 1 or method 2 (n = 10 for each method). The non-gas endospray was then used in two patients undergoing laparoscopic splenectomy with CO2 pneumoperitoneum. Intra-abdominal pressure was measured throughout the surgery. Results: Bursting pressures were similar in method 1 (246.9 ± 123.2 mmHg) and method 2 (265.5 ± 93.6 mmHg; P = 0.7082). During laparoscopic splenectomy, the non-gas endospray was successfully used to apply fibrin glue without any increase in intra-abdominal pressure. Conclusions: The novel non-gas endospray produced a strong sealing effect similar to that of a conventional gas-spray device and has thus far proved feasible in the clinical setting. |
| first_indexed | 2024-03-12T00:33:13Z |
| format | Article |
| id | doaj.art-8e63207a4c3647f195f176397f747f3f |
| institution | Directory Open Access Journal |
| issn | 0894-1939 1521-0553 |
| language | English |
| last_indexed | 2024-03-12T00:33:13Z |
| publishDate | 2020-04-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Investigative Surgery |
| spelling | doaj.art-8e63207a4c3647f195f176397f747f3f2023-09-15T10:07:29ZengTaylor & Francis GroupJournal of Investigative Surgery0894-19391521-05532020-04-0133435936410.1080/08941939.2018.15190501519050A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic SurgeryNorifumi Tsutsumi0Yoshihisa Sakaguchi1Tetsuya Kusumoto2Koji Ikejiri3Ryosuke Tsutsumi4Koichi Kimura5Soichiro Maekawa6National Hospital Organization Kyushu Medical CenterNational Hospital Organization Kyushu Medical CenterNational Hospital Organization Kyushu Medical CenterNational Hospital Organization Kyushu Medical CenterMunakata Medical Association HospitalMunakata Medical Association HospitalMunakata Medical Association HospitalPurpose: Fibrin glue and polyglycolic acid felt are used for tissue repair in various surgical procedures. However, using a spray device to apply fibrin sealant during laparoscopic surgery can increase the intraperitoneal pressure, which can cause complications such as air embolism. We developed a novel non-gas endospray for use in laparoscopic surgery. This study aimed to evaluate the sealing effect of this non-gas endospray in comparison with a conventional gas-spray device and to evaluate the safety of its application in the clinical setting. Materials and Methods: An ex vivo pressure test model was used to assess the sealing effect of the non-gas endospray (method 1) versus conventional gas-spray (method 2). A bottle was sealed with a rabbit skin sample that had been pierced nine times by a 19G needle. Each skin sample was sealed using either method 1 or method 2 (n = 10 for each method). The non-gas endospray was then used in two patients undergoing laparoscopic splenectomy with CO2 pneumoperitoneum. Intra-abdominal pressure was measured throughout the surgery. Results: Bursting pressures were similar in method 1 (246.9 ± 123.2 mmHg) and method 2 (265.5 ± 93.6 mmHg; P = 0.7082). During laparoscopic splenectomy, the non-gas endospray was successfully used to apply fibrin glue without any increase in intra-abdominal pressure. Conclusions: The novel non-gas endospray produced a strong sealing effect similar to that of a conventional gas-spray device and has thus far proved feasible in the clinical setting.http://dx.doi.org/10.1080/08941939.2018.1519050fibrin sealantlaparoscopic surgerypneumoperitoneumgas spray |
| spellingShingle | Norifumi Tsutsumi Yoshihisa Sakaguchi Tetsuya Kusumoto Koji Ikejiri Ryosuke Tsutsumi Koichi Kimura Soichiro Maekawa A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery Journal of Investigative Surgery fibrin sealant laparoscopic surgery pneumoperitoneum gas spray |
| title | A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery |
| title_full | A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery |
| title_fullStr | A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery |
| title_full_unstemmed | A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery |
| title_short | A Novel Non-Gas Endospray for Applying Fibrin Glue in Laparoscopic Surgery |
| title_sort | novel non gas endospray for applying fibrin glue in laparoscopic surgery |
| topic | fibrin sealant laparoscopic surgery pneumoperitoneum gas spray |
| url | http://dx.doi.org/10.1080/08941939.2018.1519050 |
| work_keys_str_mv | AT norifumitsutsumi anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT yoshihisasakaguchi anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT tetsuyakusumoto anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT kojiikejiri anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT ryosuketsutsumi anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT koichikimura anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT soichiromaekawa anovelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT norifumitsutsumi novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT yoshihisasakaguchi novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT tetsuyakusumoto novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT kojiikejiri novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT ryosuketsutsumi novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT koichikimura novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery AT soichiromaekawa novelnongasendosprayforapplyingfibringlueinlaparoscopicsurgery |