Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region.
We investigated linear growth and weight attained among 772 children at 10-15 months of age in the first population-based birth cohort in the Brazilian Amazon. Sociodemographic, maternal and birth characteristics were collected in interviews soon after birth at baseline. Anthropometric evaluation wa...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2019-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0220513 |
| _version_ | 1818925396088848384 |
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| author | Juliana Paghi Dal Bom Lalucha Mazzucchetti Maíra Barreto Malta Simone Ladeia-Andrade Marcia Caldas de Castro Marly Augusto Cardoso Bárbara Hatzlhoffer Lourenço MINA-Brazil Study Working Group |
| author_facet | Juliana Paghi Dal Bom Lalucha Mazzucchetti Maíra Barreto Malta Simone Ladeia-Andrade Marcia Caldas de Castro Marly Augusto Cardoso Bárbara Hatzlhoffer Lourenço MINA-Brazil Study Working Group |
| author_sort | Juliana Paghi Dal Bom |
| collection | DOAJ |
| description | We investigated linear growth and weight attained among 772 children at 10-15 months of age in the first population-based birth cohort in the Brazilian Amazon. Sociodemographic, maternal and birth characteristics were collected in interviews soon after birth at baseline. Anthropometric evaluation was conducted at 10-15 months. Multiple linear regression models were fitted for length-for-age (LAZ) and body mass index (BMI)-for-age Z scores (BAZ), considering a hierarchical conceptual framework with determinants at distal, intermediate and proximal levels, with adjustment for the child's sex and age. Mean LAZ and BAZ were 0.31 (SD: 1.13) and 0.35 (SD: 1.06), respectively. Overall, 2.2% of children were stunted and 6.6% overweight. Among socioeconomic factors, household wealth index was positively associated with LAZ (p for trend = 0.01), while children whose families received assistance from the Bolsa Família conditional cash transfer program were 0.16 Z score thinner (95% CI: -0.31, -0.00). Maternal height and BMI were positively associated with both LAZ and BAZ at 10-15 months of age (p for trend <0.001). Child's size at birth was positively related with LAZ (p<0.001 for both birth weight and length). BAZ was 0.34 (95% CI: 0.24, 0.44) higher, but 0.11 lower (95% CI: -0.21, -0.02), for each increase in 1 Z score of birth weight and length, respectively. Children with at least one reported malaria episode within the first year of life were 0.58 (95% CI: -1.05, -0.11) Z score shorter. Socioeconomic and intergenerational factors were consistently associated with LAZ and BAZ at 10-15 months of age. The occurrence of malaria was detrimental to linear growth. In a malaria endemic region, reduction of inequalities and disease burden over the first 1,000 days of life is essential for taking advantage of a critical window of opportunity that can redirect child growth trajectories toward better health and nutrition conditions in the long term. |
| first_indexed | 2024-12-20T02:40:33Z |
| format | Article |
| id | doaj.art-8e6678f088d24e989f5bc1c32d5ba39c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T02:40:33Z |
| publishDate | 2019-01-01 |
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| spelling | doaj.art-8e6678f088d24e989f5bc1c32d5ba39c2022-12-21T19:56:19ZengPublic Library of Science (PLoS)PLoS ONE1932-62032019-01-01148e022051310.1371/journal.pone.0220513Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region.Juliana Paghi Dal BomLalucha MazzucchettiMaíra Barreto MaltaSimone Ladeia-AndradeMarcia Caldas de CastroMarly Augusto CardosoBárbara Hatzlhoffer LourençoMINA-Brazil Study Working GroupWe investigated linear growth and weight attained among 772 children at 10-15 months of age in the first population-based birth cohort in the Brazilian Amazon. Sociodemographic, maternal and birth characteristics were collected in interviews soon after birth at baseline. Anthropometric evaluation was conducted at 10-15 months. Multiple linear regression models were fitted for length-for-age (LAZ) and body mass index (BMI)-for-age Z scores (BAZ), considering a hierarchical conceptual framework with determinants at distal, intermediate and proximal levels, with adjustment for the child's sex and age. Mean LAZ and BAZ were 0.31 (SD: 1.13) and 0.35 (SD: 1.06), respectively. Overall, 2.2% of children were stunted and 6.6% overweight. Among socioeconomic factors, household wealth index was positively associated with LAZ (p for trend = 0.01), while children whose families received assistance from the Bolsa Família conditional cash transfer program were 0.16 Z score thinner (95% CI: -0.31, -0.00). Maternal height and BMI were positively associated with both LAZ and BAZ at 10-15 months of age (p for trend <0.001). Child's size at birth was positively related with LAZ (p<0.001 for both birth weight and length). BAZ was 0.34 (95% CI: 0.24, 0.44) higher, but 0.11 lower (95% CI: -0.21, -0.02), for each increase in 1 Z score of birth weight and length, respectively. Children with at least one reported malaria episode within the first year of life were 0.58 (95% CI: -1.05, -0.11) Z score shorter. Socioeconomic and intergenerational factors were consistently associated with LAZ and BAZ at 10-15 months of age. The occurrence of malaria was detrimental to linear growth. In a malaria endemic region, reduction of inequalities and disease burden over the first 1,000 days of life is essential for taking advantage of a critical window of opportunity that can redirect child growth trajectories toward better health and nutrition conditions in the long term.https://doi.org/10.1371/journal.pone.0220513 |
| spellingShingle | Juliana Paghi Dal Bom Lalucha Mazzucchetti Maíra Barreto Malta Simone Ladeia-Andrade Marcia Caldas de Castro Marly Augusto Cardoso Bárbara Hatzlhoffer Lourenço MINA-Brazil Study Working Group Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. PLoS ONE |
| title | Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. |
| title_full | Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. |
| title_fullStr | Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. |
| title_full_unstemmed | Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. |
| title_short | Early determinants of linear growth and weight attained in the first year of life in a malaria endemic region. |
| title_sort | early determinants of linear growth and weight attained in the first year of life in a malaria endemic region |
| url | https://doi.org/10.1371/journal.pone.0220513 |
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