Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice

Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice

Obesity affects the function of multiple organs/tissues including the exocrine organ salivary glands. However, the effects of obesity on transcriptomes and cell compositions in the salivary glands have yet been studied by bulk RNA-sequencing and single-cell RNA-sequencing. Besides, the cell types in...

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Bibliographic Details
Main Authors:	Heping Huang, Ce Gao, Shuai Wang, Fen Wu, Jinsong Wei, Jinrong Peng
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Series:	Computational and Structural Biotechnology Journal
Subjects:	Salivary glands High-fat diet Obesity RNA-seq scRNA-seq, mouse
Online Access:	http://www.sciencedirect.com/science/article/pii/S2001037022005499

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