Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus
Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2023-03-01
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| Series: | Iranian Journal of Immunology |
| Subjects: | |
| Online Access: | https://iji.sums.ac.ir/article_49147_625fb96db13a7705124f6fcda51cd1bf.pdf |
| _version_ | 1797857631226822656 |
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| author | Yan-Lian Liang Yu Shi Yu-Qing Su Fan Wu Yanwen Liang Xiuchu Fan Jiansuo Lin Yi Liu Long Peng Jianwei Ren Shuang Liang |
| author_facet | Yan-Lian Liang Yu Shi Yu-Qing Su Fan Wu Yanwen Liang Xiuchu Fan Jiansuo Lin Yi Liu Long Peng Jianwei Ren Shuang Liang |
| author_sort | Yan-Lian Liang |
| collection | DOAJ |
| description | Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both cases, pregnancy was terminated, in weeks 33 and 23 respectively, due to a diagnosis of fetal growth retardation (FGR). To our knowledge, these are the most severe HDFN cases caused by cold-reacting IgG anti-M. |
| first_indexed | 2024-04-09T20:59:50Z |
| format | Article |
| id | doaj.art-8e6b826f790c405b93cecd364f99a10d |
| institution | Directory Open Access Journal |
| issn | 1735-1383 1735-367X |
| language | English |
| last_indexed | 2024-04-09T20:59:50Z |
| publishDate | 2023-03-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Immunology |
| spelling | doaj.art-8e6b826f790c405b93cecd364f99a10d2023-03-29T10:06:37ZengShiraz University of Medical SciencesIranian Journal of Immunology1735-13831735-367X2023-03-0120112913410.22034/iji.2023.93993.227349147Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the FetusYan-Lian Liang0Yu Shi1Yu-Qing Su2Fan Wu3Yanwen Liang4Xiuchu Fan5Jiansuo Lin6Yi Liu7Long Peng8Jianwei Ren9Shuang Liang10Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China.Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.R&D Division, Shenzhen Ritzcon Biological Technology Co., Ltd., Shenzhen, Guangdong, P.R.China.R&D Division, Shenzhen Ritzcon Biological Technology Co., Ltd., Shenzhen, Guangdong, P.R.China.R&D Division, Shenzhen Ritzcon Biological Technology Co., Ltd., Shenzhen, Guangdong, P.R.China.Guangdong Key Laboratory for Research and Development of Natural Drugs, Department of Pharmacology, Marine Medicine Research Institute, Guangdong Medical University, Zhanjiang, Guangdong, P.R.China.Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China. R&D Division, Shenzhen Ritzcon Biological Technology Co., Ltd., Shenzhen, Guangdong, P.R.China. Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, P.R.China.Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both cases, pregnancy was terminated, in weeks 33 and 23 respectively, due to a diagnosis of fetal growth retardation (FGR). To our knowledge, these are the most severe HDFN cases caused by cold-reacting IgG anti-M.https://iji.sums.ac.ir/article_49147_625fb96db13a7705124f6fcda51cd1bf.pdfanti-m antibodycold-reacting igghdfnmns blood group |
| spellingShingle | Yan-Lian Liang Yu Shi Yu-Qing Su Fan Wu Yanwen Liang Xiuchu Fan Jiansuo Lin Yi Liu Long Peng Jianwei Ren Shuang Liang Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus Iranian Journal of Immunology anti-m antibody cold-reacting igg hdfn mns blood group |
| title | Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus |
| title_full | Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus |
| title_fullStr | Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus |
| title_full_unstemmed | Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus |
| title_short | Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus |
| title_sort | maternal cold reacting immunoglobulin g anti m of mns blood group system causing hemolytic disease of the fetus |
| topic | anti-m antibody cold-reacting igg hdfn mns blood group |
| url | https://iji.sums.ac.ir/article_49147_625fb96db13a7705124f6fcda51cd1bf.pdf |
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