Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review
Primary fallopian tube carcinoma (PFTC) has characteristics similar to those of ovarian carcinoma. The typical course of PFTC metastasis includes peritoneal dissemination and pelvic and paraaortic lymph node metastasis, while inguinal lymph node metastasis is rare. Moreover, the initial presentation...
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MDPI AG
2022-04-01
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| Online Access: | https://www.mdpi.com/1648-9144/58/5/581 |
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| author | Michihide Maeda Tsuyoshi Hisa Shinya Matsuzaki Shuichi Ohe Shigenori Nagata Misooja Lee Seiji Mabuchi Shoji Kamiura |
| author_facet | Michihide Maeda Tsuyoshi Hisa Shinya Matsuzaki Shuichi Ohe Shigenori Nagata Misooja Lee Seiji Mabuchi Shoji Kamiura |
| author_sort | Michihide Maeda |
| collection | DOAJ |
| description | Primary fallopian tube carcinoma (PFTC) has characteristics similar to those of ovarian carcinoma. The typical course of PFTC metastasis includes peritoneal dissemination and pelvic and paraaortic lymph node metastasis, while inguinal lymph node metastasis is rare. Moreover, the initial presentation of PFTC with an inguinal tumor is extremely rare. A 77-year-old postmenopausal woman presented with a massive 12-cm inguinal subcutaneous tumor. After tumor resection, histopathological and immunohistochemical analysis showed that the tumor was a high-grade serous carcinoma of gynecological origin. Subsequent surgery for total hysterectomy with bilateral salpingo-oophorectomy revealed that the tumor developed in the fallopian tube. She received adjuvant chemotherapy with carboplatin and paclitaxel, followed by maintenance therapy with niraparib. There has been no recurrence or metastasis 9 months after the second surgery. We reviewed the literature for cases of PFTC and ovarian carcinoma that initially presented with an inguinal tumor. In compliance with the Preferred Reporting Items for Systematic Reviews guidelines, a systematic literature search was performed through 31 January 2022 using the PubMed and Google scholar databases and identified 14 cases. In half of them, it was difficult to identify the primary site using preoperative imaging modalities. Disease recurrence occurred in two cases; thus, the prognosis of this type of PFTC appears to be good. |
| first_indexed | 2024-03-10T03:28:07Z |
| format | Article |
| id | doaj.art-8e6c8a86b9d343759282d1d93cd71e25 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T03:28:07Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-8e6c8a86b9d343759282d1d93cd71e252023-11-23T12:02:49ZengMDPI AGMedicina1010-660X1648-91442022-04-0158558110.3390/medicina58050581Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature ReviewMichihide Maeda0Tsuyoshi Hisa1Shinya Matsuzaki2Shuichi Ohe3Shigenori Nagata4Misooja Lee5Seiji Mabuchi6Shoji Kamiura7Department of Gynecology, Osaka International Cancer Institute, Osaka 541-8567, JapanDepartment of Gynecology, Osaka International Cancer Institute, Osaka 541-8567, JapanDepartment of Gynecology, Osaka International Cancer Institute, Osaka 541-8567, JapanDepartment of Dermatologic Oncology, Osaka International Cancer Institute, Osaka 541-8567, JapanDepartment of Clinical Pathology, Osaka International Cancer Institute, Osaka 541-8567, JapanDepartment of Forensic Medicine, School of Medicine, Kindai University, Osaka 589-8511, JapanDepartment of Gynecology, Osaka International Cancer Institute, Osaka 541-8567, JapanDepartment of Gynecology, Osaka International Cancer Institute, Osaka 541-8567, JapanPrimary fallopian tube carcinoma (PFTC) has characteristics similar to those of ovarian carcinoma. The typical course of PFTC metastasis includes peritoneal dissemination and pelvic and paraaortic lymph node metastasis, while inguinal lymph node metastasis is rare. Moreover, the initial presentation of PFTC with an inguinal tumor is extremely rare. A 77-year-old postmenopausal woman presented with a massive 12-cm inguinal subcutaneous tumor. After tumor resection, histopathological and immunohistochemical analysis showed that the tumor was a high-grade serous carcinoma of gynecological origin. Subsequent surgery for total hysterectomy with bilateral salpingo-oophorectomy revealed that the tumor developed in the fallopian tube. She received adjuvant chemotherapy with carboplatin and paclitaxel, followed by maintenance therapy with niraparib. There has been no recurrence or metastasis 9 months after the second surgery. We reviewed the literature for cases of PFTC and ovarian carcinoma that initially presented with an inguinal tumor. In compliance with the Preferred Reporting Items for Systematic Reviews guidelines, a systematic literature search was performed through 31 January 2022 using the PubMed and Google scholar databases and identified 14 cases. In half of them, it was difficult to identify the primary site using preoperative imaging modalities. Disease recurrence occurred in two cases; thus, the prognosis of this type of PFTC appears to be good.https://www.mdpi.com/1648-9144/58/5/581primary fallopian tube carcinomainguinal tumoringuinal lymph node metastasisserous carcinoma |
| spellingShingle | Michihide Maeda Tsuyoshi Hisa Shinya Matsuzaki Shuichi Ohe Shigenori Nagata Misooja Lee Seiji Mabuchi Shoji Kamiura Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review Medicina primary fallopian tube carcinoma inguinal tumor inguinal lymph node metastasis serous carcinoma |
| title | Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review |
| title_full | Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review |
| title_fullStr | Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review |
| title_full_unstemmed | Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review |
| title_short | Primary Fallopian Tube Carcinoma Presenting with a Massive Inguinal Tumor: A Case Report and Literature Review |
| title_sort | primary fallopian tube carcinoma presenting with a massive inguinal tumor a case report and literature review |
| topic | primary fallopian tube carcinoma inguinal tumor inguinal lymph node metastasis serous carcinoma |
| url | https://www.mdpi.com/1648-9144/58/5/581 |
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