Different siderophores contribute to the high-pathogenicity phenotype in Yersinia
capture and transport in bacteria. At least one endogenous siderophore system, yersiniabactin, is known to be involved in iron acquisition in highly virulent Yersiniae . Its inactivation in Y. pestis and Y. enterocolitica subsp. enterocolitica results in significant attenuation of virulence. However...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2013-09-01
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| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/62 |
| _version_ | 1797220883102695424 |
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| author | A. Rakin D. Garzetti |
| author_facet | A. Rakin D. Garzetti |
| author_sort | A. Rakin |
| collection | DOAJ |
| description | capture and transport in bacteria. At least one endogenous siderophore system, yersiniabactin, is known to be involved in iron acquisition in highly virulent Yersiniae . Its inactivation in Y. pestis and Y. enterocolitica subsp. enterocolitica results in significant attenuation of virulence. However, the yersiniabactin is not present in all highly virulent Yersiniae. Indeed, the large group of Y. pseudotuberculosis serotypes O2, O3, O4, O5 as well as serotype O1 Far East Scarlet like fever (FESLF) strains carry an alternative, iron acquisition system, pseudochelin, encoded by the Yersinia non-ribosomal peptide ynp locus. Thus, the yersiniabactin activity is not the only one associated with the high-pathogenicity phenotype of the human pathogenic Yersiniae . |
| first_indexed | 2024-03-08T13:43:33Z |
| format | Article |
| id | doaj.art-8e6cac12192d46d99a7df42e65501bff |
| institution | Directory Open Access Journal |
| issn | 0370-1069 2658-719X |
| language | Russian |
| last_indexed | 2024-04-24T12:56:37Z |
| publishDate | 2013-09-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj.art-8e6cac12192d46d99a7df42e65501bff2024-04-05T16:47:09ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2013-09-0103586210.21055/0370-1069-2013-3-58-6262Different siderophores contribute to the high-pathogenicity phenotype in YersiniaA. Rakin0D. Garzetti1Max von Pettenkofer-InstituteMax von Pettenkofer-Institutecapture and transport in bacteria. At least one endogenous siderophore system, yersiniabactin, is known to be involved in iron acquisition in highly virulent Yersiniae . Its inactivation in Y. pestis and Y. enterocolitica subsp. enterocolitica results in significant attenuation of virulence. However, the yersiniabactin is not present in all highly virulent Yersiniae. Indeed, the large group of Y. pseudotuberculosis serotypes O2, O3, O4, O5 as well as serotype O1 Far East Scarlet like fever (FESLF) strains carry an alternative, iron acquisition system, pseudochelin, encoded by the Yersinia non-ribosomal peptide ynp locus. Thus, the yersiniabactin activity is not the only one associated with the high-pathogenicity phenotype of the human pathogenic Yersiniae .https://journal.microbe.ru/jour/article/view/62патогенные иерсиниифенотип высокой патогенностисидерофорыpathogenic yersiniaehigh-pathogenicity phenotypesiderophores |
| spellingShingle | A. Rakin D. Garzetti Different siderophores contribute to the high-pathogenicity phenotype in Yersinia Проблемы особо опасных инфекций патогенные иерсинии фенотип высокой патогенности сидерофоры pathogenic yersiniae high-pathogenicity phenotype siderophores |
| title | Different siderophores contribute to the high-pathogenicity phenotype in Yersinia |
| title_full | Different siderophores contribute to the high-pathogenicity phenotype in Yersinia |
| title_fullStr | Different siderophores contribute to the high-pathogenicity phenotype in Yersinia |
| title_full_unstemmed | Different siderophores contribute to the high-pathogenicity phenotype in Yersinia |
| title_short | Different siderophores contribute to the high-pathogenicity phenotype in Yersinia |
| title_sort | different siderophores contribute to the high pathogenicity phenotype in yersinia |
| topic | патогенные иерсинии фенотип высокой патогенности сидерофоры pathogenic yersiniae high-pathogenicity phenotype siderophores |
| url | https://journal.microbe.ru/jour/article/view/62 |
| work_keys_str_mv | AT arakin differentsiderophorescontributetothehighpathogenicityphenotypeinyersinia AT dgarzetti differentsiderophorescontributetothehighpathogenicityphenotypeinyersinia |