Parp Inhibitors and Radiotherapy: A New Combination for Prostate Cancer (Systematic Review)

Parp Inhibitors and Radiotherapy: A New Combination for Prostate Cancer (Systematic Review)

PARPi, in combination with ionizing radiation, has demonstrated the ability to enhance cellular radiosensitivity in different tumors. The rationale is that the exposure to radiation leads to both physical and biochemical damage to DNA, prompting cells to initiate three primary mechanisms for DNA rep...

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Bibliographic Details
Main Authors: Inés Rivero Belenchón, Carmen Belen Congregado Ruiz, Carmen Saez, Ignacio Osman García, Rafael Antonio Medina López
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
PARP inhibitors
radiotherapy
prostate cancer
Online Access:https://www.mdpi.com/1422-0067/24/16/12978

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