HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue

Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. The aim of this investigation was to determine the e...

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Bibliographic Details
Main Authors:	Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders
Format:	Article
Language:	English
Published:	Elsevier 2021-11-01
Series:	Molecular Metabolism
Subjects:	Mitochondria Stress response Obesity Glucose homeostasis Insulin resistance Adipose tissue
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877821001216

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