NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells

NFE2L2 and STAT3 Converge on Common Targets to Promote Survival of Primary Lymphoma Cells

NFE2L2 and STAT3 are key pro-survival molecules, and thus, their targeting may represent a promising anti-cancer strategy. In this study, we found that a positive feedback loop occurred between them and provided evidence that their concomitant inhibition efficiently impaired the survival of PEL cell...

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Bibliographic Details
Main Authors: Andrea Arena, Michele Di Crosta, Roberta Gonnella, Roberta Zarrella, Maria Anele Romeo, Rossella Benedetti, Maria Saveria Gilardini Montani, Roberta Santarelli, Gabriella D’Orazi, Mara Cirone
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
PEL
STAT3
NRF2
HSPs
DDR
p62/SQSTM1
Online Access:https://www.mdpi.com/1422-0067/24/14/11598

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