A clinically useful and biologically informative genomic classifier for papillary thyroid cancer

A clinically useful and biologically informative genomic classifier for papillary thyroid cancer

Clinical management of papillary thyroid cancer depends on estimations of prognosis. Standard care, which relies on prognostication based on clinicopathologic features, is inaccurate. We applied a machine learning algorithm (HighLifeR) to 502 cases annotated by The Cancer Genome Atlas Project to der...

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Bibliographic Details
Main Authors: Steven Craig, Cynthia Stretch, Farshad Farshidfar, Dropen Sheka, Nikolay Alabi, Ashar Siddiqui, Karen Kopciuk, Young Joo Park, Moosa Khalil, Faisal Khan, Adrian Harvey, Oliver F. Bathe
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
prognosis
biomarker
papillary thyroid cancer
machine learning
risk stratification
EZH2
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1220617/full

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