TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS
Introduction. The preliminary study of new developed pumps for circulatory support on the hydrodynamic circulation model is an important step in the process of their designing. Hydrodynamic circulation models that can closely imitate cardio – vascular system are important to defi ne the range of eff...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2015-10-01
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| Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/564 |
| _version_ | 1797872082137120768 |
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| author | G. P. Itkin A. A. Drobyshev O. Yu. Dmitrieva A. S. Buchnev A. A. Sysoev |
| author_facet | G. P. Itkin A. A. Drobyshev O. Yu. Dmitrieva A. S. Buchnev A. A. Sysoev |
| author_sort | G. P. Itkin |
| collection | DOAJ |
| description | Introduction. The preliminary study of new developed pumps for circulatory support on the hydrodynamic circulation model is an important step in the process of their designing. Hydrodynamic circulation models that can closely imitate cardio – vascular system are important to defi ne the range of effective functioning of the pumps under normal and heart disease conditions which is of great importance for defi ning the mode of these pumps in real clinical conditions.The aim of study is to create a new hydrodynamic circulation model of the systemic circulation to study the processes of interaction of heart left ventricle and continuous – fl ow pumps.Materials and methods. The main components of the mock circulation model (arterial and venous blocks) are designed as closed reservoirs with an air bag providing the necessary elasticity value of these reservoirs. The heart left ventricle was simulated with an artifi cial heart ventricle with a pneumatic drive Sinus-IS which allows to change its options in a wide range. As a test pump we used the fi rst native implantable axial pump VISH – 1. In the course of research we made the registration and recording of the basic hemodynamic parameters (pressure, fl ow) with a multichannel module Pumpax for the measurement of pressure parameters.Results. The designed circulation model allows to adequately reproduce the main hemodynamic parameters of the circulatory system in normal (arterial pressure – 110/77 mmHg, left atrium pressure – 7 mmHg and cardiac output – 4.2 l/min) and heart failure conditions (arterial pressure – 79/53 mmHg, left atrium pressure – 15 mmHg and cardiac output – 3.1 l/min). On the circulation model the interaction of heart left ventricle and continuous-fl ow pump in heart failure simulation was studied. The dynamics of the main circulation fi gures is shown under conditions of changing of the pump rotor speed. Meanwhile, the conditions of the closing of aortic valve are identifi ed which is important for theclinical use of this pump. Using a special separately fl exible camera on the pump inlet we modeled phenomena of negative pressure leading to unstable pump operation and reduction of pump fl ow.Conclusion. Characteristics of the developed hydrodynamic circulation model allow us to reproduce parameters of systemic circulation in a wide range and to use it in designing of new pumps for circulatory support. |
| first_indexed | 2024-04-10T00:53:09Z |
| format | Article |
| id | doaj.art-8e748b62809f40cc81806ab90a0496ba |
| institution | Directory Open Access Journal |
| issn | 1995-1191 |
| language | Russian |
| last_indexed | 2024-04-10T00:53:09Z |
| publishDate | 2015-10-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Vestnik Transplantologii i Iskusstvennyh Organov |
| spelling | doaj.art-8e748b62809f40cc81806ab90a0496ba2023-03-13T10:37:22ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912015-10-01173434910.15825/1995-1191-2015-3-43-49487TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONSG. P. Itkin0A. A. Drobyshev1O. Yu. Dmitrieva2A. S. Buchnev3A. A. Sysoev4V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow, Russian FederationIntroduction. The preliminary study of new developed pumps for circulatory support on the hydrodynamic circulation model is an important step in the process of their designing. Hydrodynamic circulation models that can closely imitate cardio – vascular system are important to defi ne the range of effective functioning of the pumps under normal and heart disease conditions which is of great importance for defi ning the mode of these pumps in real clinical conditions.The aim of study is to create a new hydrodynamic circulation model of the systemic circulation to study the processes of interaction of heart left ventricle and continuous – fl ow pumps.Materials and methods. The main components of the mock circulation model (arterial and venous blocks) are designed as closed reservoirs with an air bag providing the necessary elasticity value of these reservoirs. The heart left ventricle was simulated with an artifi cial heart ventricle with a pneumatic drive Sinus-IS which allows to change its options in a wide range. As a test pump we used the fi rst native implantable axial pump VISH – 1. In the course of research we made the registration and recording of the basic hemodynamic parameters (pressure, fl ow) with a multichannel module Pumpax for the measurement of pressure parameters.Results. The designed circulation model allows to adequately reproduce the main hemodynamic parameters of the circulatory system in normal (arterial pressure – 110/77 mmHg, left atrium pressure – 7 mmHg and cardiac output – 4.2 l/min) and heart failure conditions (arterial pressure – 79/53 mmHg, left atrium pressure – 15 mmHg and cardiac output – 3.1 l/min). On the circulation model the interaction of heart left ventricle and continuous-fl ow pump in heart failure simulation was studied. The dynamics of the main circulation fi gures is shown under conditions of changing of the pump rotor speed. Meanwhile, the conditions of the closing of aortic valve are identifi ed which is important for theclinical use of this pump. Using a special separately fl exible camera on the pump inlet we modeled phenomena of negative pressure leading to unstable pump operation and reduction of pump fl ow.Conclusion. Characteristics of the developed hydrodynamic circulation model allow us to reproduce parameters of systemic circulation in a wide range and to use it in designing of new pumps for circulatory support.https://journal.transpl.ru/vtio/article/view/564hydrodynamic circulation modelarterial reservoirvenous reservoirhydrodynamic resistanceaxialpumpphysiological normheart failure |
| spellingShingle | G. P. Itkin A. A. Drobyshev O. Yu. Dmitrieva A. S. Buchnev A. A. Sysoev TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS Vestnik Transplantologii i Iskusstvennyh Organov hydrodynamic circulation model arterial reservoir venous reservoir hydrodynamic resistance axial pump physiological norm heart failure |
| title | TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS |
| title_full | TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS |
| title_fullStr | TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS |
| title_full_unstemmed | TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS |
| title_short | TESTING THE INTERACTION OF HEART LEFT VENTRICLE AND CONTINUOUS-FLOW PUMP ON A MOCK CIRCULATION MODEL UNDER NORMAL AND PATHOLOGICAL CONDITIONS |
| title_sort | testing the interaction of heart left ventricle and continuous flow pump on a mock circulation model under normal and pathological conditions |
| topic | hydrodynamic circulation model arterial reservoir venous reservoir hydrodynamic resistance axial pump physiological norm heart failure |
| url | https://journal.transpl.ru/vtio/article/view/564 |
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